ID A0A2I2ZAP2_GORGO Unreviewed; 456 AA.
AC A0A2I2ZAP2;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=RCC1 like {ECO:0000313|Ensembl:ENSGGOP00000044338.1};
GN Name=RCC1L {ECO:0000313|Ensembl:ENSGGOP00000044338.1};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000044338.1, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000044338.1, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000044338.1, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000044338.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030052755; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030052756; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030052757; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030052758; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030052759; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030052760; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030052761; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030052762; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030052763; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004045635.1; XM_004045587.2.
DR AlphaFoldDB; A0A2I2ZAP2; -.
DR STRING; 9593.ENSGGOP00000044338; -.
DR Ensembl; ENSGGOT00000045115.1; ENSGGOP00000044338.1; ENSGGOG00000016055.3.
DR GeneTree; ENSGT00940000157317; -.
DR InParanoid; A0A2I2ZAP2; -.
DR OMA; GSFCMAL; -.
DR Proteomes; UP000001519; Chromosome 7.
DR Bgee; ENSGGOG00000016055; Expressed in heart and 5 other cell types or tissues.
DR GO; GO:0005743; C:mitochondrial inner membrane; IBA:GO_Central.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IBA:GO_Central.
DR GO; GO:0019843; F:rRNA binding; IBA:GO_Central.
DR GO; GO:0008053; P:mitochondrial fusion; IEA:Ensembl.
DR GO; GO:0070131; P:positive regulation of mitochondrial translation; IBA:GO_Central.
DR Gene3D; 2.130.10.30; Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II; 2.
DR InterPro; IPR009091; RCC1/BLIP-II.
DR InterPro; IPR000408; Reg_chr_condens.
DR PANTHER; PTHR46337; RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN; 1.
DR PANTHER; PTHR46337:SF1; RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN; 1.
DR Pfam; PF00415; RCC1; 1.
DR Pfam; PF13540; RCC1_2; 3.
DR PRINTS; PR00633; RCCNDNSATION.
DR SUPFAM; SSF50985; RCC1/BLIP-II; 1.
DR PROSITE; PS00626; RCC1_2; 1.
DR PROSITE; PS50012; RCC1_3; 5.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001519}.
FT REPEAT 129..192
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 193..248
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 249..301
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 302..354
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
FT REPEAT 355..412
FT /note="RCC1"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00235"
SQ SEQUENCE 456 AA; 49212 MW; A51D264B7C405F61 CRC64;
MALVALVAGA RLGRRLSGPG LGRGHWTAAG RSRSRREAAE AEAEVPVVQY VGERAARADR
VFVWGFSFSG ALGVPSFVVP SSGPGPRAGA RPRRRIQPVP YRLELDQKIS SAACGYGFTL
LSSKTADVTK VWGMGLNKDS QLGFHRSRKD KTRGYEYVLE PSPVSLPLDR PQETRVLQVS
CGRAHSLVLT DREGVFSMGN NSYGQCGRKV VENEIYSESH RVHRMQDFDG QVVQVACGQD
HSLFLTDKGE VYSCGWGADG QTGLGHYNIT SSPTKLGGDL AGVNVIQVAT YGDCCLAVST
DGGLFGWGNS EYLQLASVTD STQVNVPRCL HFSGVGKVRQ AACGGTGCAV LNGEGHVFVW
GYGILGKGPN LVESAVPEMI PPTLFGLTEF NPEIQVSRIR CGLSHFAALT NKGELFVWGK
NIRGCLGIGR LEDQYFPWRV RLAGEVLRMD AKSRVT
//
