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Database: UniProt
Entry: A0A2I2ZCD7_GORGO
LinkDB: A0A2I2ZCD7_GORGO
Original site: A0A2I2ZCD7_GORGO 
ID   A0A2I2ZCD7_GORGO        Unreviewed;      1559 AA.
AC   A0A2I2ZCD7;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   31-JUL-2019, entry version 11.
DE   SubName: Full=Calmodulin regulated spectrin associated protein 1 {ECO:0000313|Ensembl:ENSGGOP00000044914};
GN   Name=CAMSAP1 {ECO:0000313|Ensembl:ENSGGOP00000044914};
OS   Gorilla gorilla gorilla (Western lowland gorilla).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Gorilla.
OX   NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000044914, ECO:0000313|Proteomes:UP000001519};
RN   [1] {ECO:0000313|Ensembl:ENSGGOP00000044914, ECO:0000313|Proteomes:UP000001519}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Scally A.;
RT   "Insights into the evolution of the great apes provided by the gorilla
RT   genome.";
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGGOP00000044914}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=22398555; DOI=10.1038/nature10842;
RA   Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA   Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA   McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C.,
RA   Xue Y., Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V.,
RA   Beal K., Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A.,
RA   Gu Y., Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K.,
RA   Lunter G., Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D.,
RA   Phillips A.D., Prado-Martinez J., Rogers A.S., Sajjadian S.,
RA   Schmidt D., Shaw K., Simpson J.T., Stenson P.D., Turner D.J.,
RA   Vigilant L., Vilella A.J., Whitener W., Zhu B., Cooper D.N.,
RA   de Jong P., Dermitzakis E.T., Eichler E.E., Flicek P., Goldman N.,
RA   Mundy N.I., Ning Z., Odom D.T., Ponting C.P., Quail M.A., Ryder O.A.,
RA   Searle S.M., Warren W.C., Wilson R.K., Schierup M.H., Rogers J.,
RA   Tyler-Smith C., Durbin R.;
RT   "Insights into hominid evolution from the gorilla genome sequence.";
RL   Nature 483:169-175(2012).
RN   [3] {ECO:0000313|Ensembl:ENSGGOP00000044914}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2018) to UniProtKB.
CC   -!- DOMAIN: The CKK domain binds microtubules. {ECO:0000256|PROSITE-
CC       ProRule:PRU00841}.
CC   -!- SIMILARITY: Belongs to the CAMSAP1 family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00841}.
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DR   EMBL; CABD030067349; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CABD030067350; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CABD030067351; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSGGOT00000042743; ENSGGOP00000044914; ENSGGOG00000000387.
DR   GeneTree; ENSGT00950000182975; -.
DR   OMA; NKEDECG; -.
DR   Proteomes; UP000001519; Chromosome 9.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-UniRule.
DR   GO; GO:0005516; F:calmodulin binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0030507; F:spectrin binding; IEA:InterPro.
DR   GO; GO:0031175; P:neuron projection development; IEA:InterPro.
DR   Gene3D; 3.10.20.360; -; 1.
DR   InterPro; IPR032940; CAMSAP.
DR   InterPro; IPR031372; CAMSAP_CC1.
DR   InterPro; IPR022613; CAMSAP_CH.
DR   InterPro; IPR001715; CH-domain.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR038209; CKK_dom_sf.
DR   InterPro; IPR014797; CKK_domain.
DR   InterPro; IPR011033; PRC_barrel-like_sf.
DR   PANTHER; PTHR21595; PTHR21595; 1.
DR   Pfam; PF17095; CAMSAP_CC1; 1.
DR   Pfam; PF11971; CAMSAP_CH; 1.
DR   Pfam; PF08683; CAMSAP_CKK; 1.
DR   SMART; SM01051; CAMSAP_CKK; 1.
DR   SUPFAM; SSF47576; SSF47576; 1.
DR   SUPFAM; SSF50346; SSF50346; 1.
DR   PROSITE; PS50021; CH; 1.
DR   PROSITE; PS51508; CKK; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001519};
KW   Microtubule {ECO:0000256|PROSITE-ProRule:PRU00841};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001519}.
FT   DOMAIN      173    288       Calponin-homology (CH).
FT                                {ECO:0000259|PROSITE:PS50021}.
FT   DOMAIN     1420   1554       CKK. {ECO:0000259|PROSITE:PS51508}.
FT   REGION      311    343       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      383    415       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      560    594       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      729    765       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      782    827       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     1031   1118       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     1262   1405       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COILED      139    159       {ECO:0000256|SAM:Coils}.
FT   COILED      832    862       {ECO:0000256|SAM:Coils}.
FT   COILED      974   1001       {ECO:0000256|SAM:Coils}.
FT   COMPBIAS    315    330       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    389    405       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    562    581       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    729    747       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    748    765       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    782    817       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS   1262   1307       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS   1339   1381       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS   1391   1405       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   1559 AA;  173518 MW;  9C197778786E3885 CRC64;
     NIPEDLRDPF YVDQYEQEHI KPPVIKLLLS SELYCRVCSL ILKGDQVAAL QGHQSVIQAL
     SRKGIYVMES DDTPVTESDL SRAPIKMSAH MAMVDALMMA YTVEMISIEK VVASVKRFST
     FSASKELPYD LEDAMVFWIN KVNLKMREIT EKEVKLKQQL LESPAHQKSP SKWYWKLVPV
     RYRREHLSAR QSPYFPLLED LMRDGSDGAA LLAVIHYYCP EQMKLDDICL KEVTSMADSL
     YNIRLLREFS NEYLNKCFYL TLEDMLYAPL VLKPNVMVFI AELFWWFENV KPDFVQPRDV
     QELKDAKTVL HQKSSRPPVP ISNATKRSFL GSPAAGTPAD LQPPMQLPAE GCHRHYLHPE
     EPEYLGKGTA AFSPSHPLLP LRQKQQKSIQ GEDIPDQRHR SNSLTRVDGQ PRGAAIAWPE
     KKTRPASQPT PFALHHAASC EVDPSSGDSI SLARSISKDS LASNIVNLTP QNQPHPTATK
     SHGKSLLSNV SIEDEEEELV AIVRADVVPQ HADPEFPRAS PRALGLTANA RSPQGQLDTS
     ESKPDSFFLE PLMPAVLKPA KEKQVITKED ERGEGRPRSI VSRRPSEGPQ PLVRRKMTGS
     RDLNRTFTPI PCSEFPMGID PTETGPQSVE TAGEVCGGPL ALGGFDLFAQ GPSTDGFFLH
     VGRADEDTEG RLYVSCSKSP NSHDSEPWTL LRQDSDSDVV DIDEAEHDFM GEVHPVVLSR
     YIGEEESAKL QEDMKVKEHE DKDDASGRSS PCLSTASQMS SVSMASGSVK MTSFAERKLQ
     RLNSCETKSS TSSSQKTTPD ASESCPAPLT TWRQKREQSP SQHGRDPASL LASELVQLHM
     QLEEKRRAIE AQKKKMEALS ARQRLKLGKA AFLHVVKKGK AEAAPPLRPE HFAKEYSQHN
     GEDCGDAVSK TEDFLVKEEQ REELLHEPQD VDKESLAFAQ QHKAKDPVAL HELERNKVLS
     AALLEDAVGE VVDVNECDLS IEKLNETIST LQQAILKISQ QQEQLLMKSP TVPVPGSKNN
     SQEHKVKAPV HFVEPLSPTG VAGHRKAPRL GQGRNSRSGR PAELKVPKDR PQGSSRSKTP
     TPSVETLPHL RPFPASSHPR TPTDPGLDGA LEPSGDPHGK CLFDSYRLHD ESNQRTLTLS
     SSKDANILSE QMSLKEVLDA SVKEVGPSSS DVSGKESVPV EEPLRSRASL IEVDLSDLKA
     PDEDGELASL DGSADLVSEG DQKPGVGFFF KDEQKAEDEL AKKRAAFLLK QQRKAEEARV
     RKQQLEAEVE LKRDEARRKA EEDRVRKEEE KARRELIKQE YLRRKQQQIL EEQGLGKPKS
     KPKKPRPKSV HREESCSDSG TKCSSTPDNL SRTQSGSSLS LASAATTEPE SVHSGGTPSQ
     RVESMEALPI LSRNPSRSTD RDWETASAAS SLASVAEYTG PKLFKEPSSK SNKPIIHNAI
     SHCCLAGKVN EPHKNSILEE LEKCDANHYI ILFRDAGCQF RALYCYYPDT EEIYKLTGTG
     PKNITKKMID KLYKYSSDRK QFNLIPAKTM SVSVDALTIH NHLWQPKRPA VPKKAQTRK
//
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