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Database: UniProt
Entry: A0A2I2ZPY2_GORGO
LinkDB: A0A2I2ZPY2_GORGO
Original site: A0A2I2ZPY2_GORGO 
ID   A0A2I2ZPY2_GORGO        Unreviewed;       476 AA.
AC   A0A2I2ZPY2;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   31-JUL-2019, entry version 8.
DE   SubName: Full=Epsin 2 {ECO:0000313|Ensembl:ENSGGOP00000049288};
GN   Name=EPN2 {ECO:0000313|Ensembl:ENSGGOP00000049288};
OS   Gorilla gorilla gorilla (Western lowland gorilla).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Gorilla.
OX   NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000049288, ECO:0000313|Proteomes:UP000001519};
RN   [1] {ECO:0000313|Ensembl:ENSGGOP00000049288, ECO:0000313|Proteomes:UP000001519}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Scally A.;
RT   "Insights into the evolution of the great apes provided by the gorilla
RT   genome.";
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGGOP00000049288}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=22398555; DOI=10.1038/nature10842;
RA   Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA   Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA   McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C.,
RA   Xue Y., Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V.,
RA   Beal K., Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A.,
RA   Gu Y., Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K.,
RA   Lunter G., Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D.,
RA   Phillips A.D., Prado-Martinez J., Rogers A.S., Sajjadian S.,
RA   Schmidt D., Shaw K., Simpson J.T., Stenson P.D., Turner D.J.,
RA   Vigilant L., Vilella A.J., Whitener W., Zhu B., Cooper D.N.,
RA   de Jong P., Dermitzakis E.T., Eichler E.E., Flicek P., Goldman N.,
RA   Mundy N.I., Ning Z., Odom D.T., Ponting C.P., Quail M.A., Ryder O.A.,
RA   Searle S.M., Warren W.C., Wilson R.K., Schierup M.H., Rogers J.,
RA   Tyler-Smith C., Durbin R.;
RT   "Insights into hominid evolution from the gorilla genome sequence.";
RL   Nature 483:169-175(2012).
RN   [3] {ECO:0000313|Ensembl:ENSGGOP00000049288}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2018) to UniProtKB.
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DR   EMBL; CABD030039039; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CABD030039040; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSGGOT00000058479; ENSGGOP00000049288; ENSGGOG00000016972.
DR   GeneTree; ENSGT00940000157239; -.
DR   Proteomes; UP000001519; Chromosome 5.
DR   GO; GO:0030128; C:clathrin coat of endocytic vesicle; IEA:InterPro.
DR   GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR   Gene3D; 1.25.40.90; -; 1.
DR   InterPro; IPR013809; ENTH.
DR   InterPro; IPR008942; ENTH_VHS.
DR   InterPro; IPR027319; Epsin-2_metazoa.
DR   InterPro; IPR003903; UIM_dom.
DR   PANTHER; PTHR12276:SF50; PTHR12276:SF50; 1.
DR   Pfam; PF01417; ENTH; 1.
DR   SMART; SM00273; ENTH; 1.
DR   SMART; SM00726; UIM; 2.
DR   SUPFAM; SSF48464; SSF48464; 1.
DR   PROSITE; PS50942; ENTH; 1.
DR   PROSITE; PS50330; UIM; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001519};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001519}.
FT   DOMAIN       12    144       ENTH. {ECO:0000259|PROSITE:PS50942}.
FT   REGION      163    214       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      256    275       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      342    439       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COILED       10     30       {ECO:0000256|SAM:Coils}.
FT   COILED      123    143       {ECO:0000256|SAM:Coils}.
FT   COMPBIAS    163    186       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    356    372       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    397    424       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   476 AA;  52238 MW;  6D3DC97239C63DE4 CRC64;
     MTTSSIRRQM KNIVNNYSEA EIKVREATSN DPWGPSSSLM TEIADLTYNV VAFSEIMSMV
     WKRLNDHGKN WRHVYKALTL LDYLIKTGSE RVAQQCRENI FAIQTLKDFQ YIDRDGKDQG
     INVREKSKQL VALLKDEERL KAERAQALKT KERMAQVATG MGSNQITFGR GSSQPNLSTS
     HSEQEYGKAG GSPASYHGSP EASLCPQHRT GAPLGQSEEL QPLSQRHPFL PHLGLASHGN
     GMWSPCLLHM MTWSSPTATS PRVSSELEQA RPQTSGEEEL QLQLALAMSR EVAEQEERLR
     RGDDLRLQMA LEESRRDTVK IPKKKEHGSL PQQTTLLDLM DALPSSGPAA QKAEPWGPSA
     STNQTNPWGG PAAPASTSDP WPSFGTKPAA SIDPWGVPTG ASTQSVPKNS DPWAASQQPA
     SSAGKRASDA WGAVSTTKPV SVSGSFELFS NLNGTIKDDF SEFDNLRTSK KTGMYR
//
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