ID   A0A2I2ZST4_GORGO        Unreviewed;       241 AA.
AC   A0A2I2ZST4;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Tropomyosin 3 {ECO:0008006|Google:ProtNLM};
OS   Gorilla gorilla gorilla (Western lowland gorilla).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Gorilla.
OX   NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000050294.1, ECO:0000313|Proteomes:UP000001519};
RN   [1] {ECO:0000313|Ensembl:ENSGGOP00000050294.1, ECO:0000313|Proteomes:UP000001519}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Scally A.;
RT   "Insights into the evolution of the great apes provided by the gorilla
RT   genome.";
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGGOP00000050294.1, ECO:0000313|Proteomes:UP000001519}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=22398555; DOI=10.1038/nature10842;
RA   Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA   Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA   McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA   Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA   Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA   Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA   Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA   Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA   Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA   Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA   Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA   Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA   Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT   "Insights into hominid evolution from the gorilla genome sequence.";
RL   Nature 483:169-175(2012).
RN   [3] {ECO:0000313|Ensembl:ENSGGOP00000050294.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000256|ARBA:ARBA00004245}.
CC   -!- SIMILARITY: Belongs to the tropomyosin family.
CC       {ECO:0000256|ARBA:ARBA00009036}.
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DR   EMBL; CABD030019044; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A2I2ZST4; -.
DR   STRING; 9593.ENSGGOP00000050294; -.
DR   Ensembl; ENSGGOT00000046398.1; ENSGGOP00000050294.1; ENSGGOG00000040528.1.
DR   GeneTree; ENSGT01030000234542; -.
DR   InParanoid; A0A2I2ZST4; -.
DR   OMA; HVRECEH; -.
DR   Proteomes; UP000001519; Chromosome 2B.
DR   Bgee; ENSGGOG00000040528; Expressed in liver and 1 other cell type or tissue.
DR   GO; GO:0005884; C:actin filament; IBA:GO_Central.
DR   GO; GO:0051015; F:actin filament binding; IBA:GO_Central.
DR   GO; GO:0007015; P:actin filament organization; IBA:GO_Central.
DR   GO; GO:0006936; P:muscle contraction; IBA:GO_Central.
DR   Gene3D; 1.20.5.170; -; 1.
DR   Gene3D; 1.20.5.370; -; 1.
DR   InterPro; IPR000533; Tropomyosin.
DR   InterPro; IPR014751; XRCC4-like_C.
DR   PANTHER; PTHR19269:SF76; -; 1.
DR   PANTHER; PTHR19269; TROPOMYOSIN; 1.
DR   Pfam; PF00261; Tropomyosin; 1.
DR   PRINTS; PR00194; TROPOMYOSIN.
DR   SUPFAM; SSF57997; Tropomyosin; 1.
PE   3: Inferred from homology;
KW   Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001519}.
FT   COILED          7..90
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          133..230
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   241 AA;  27917 MW;  D3A41D8EFB0DEB21 CRC64;
     MAEITTIEAV KCKIQVLQQQ ADDAEERAEH LQQAREQAEA EVASLNCRIQ LVEEELDRAQ
     ERLATALQKL EEAEKAADES DRGMKVIENR ALKDEEKMEL QEIQLQEAKH IAEEPDRKYE
     EVAHKLVIIE GDLEGTEERA ELGESRCQEM DEQIRLMDQN LKCLSAAEEK YSEKEDKYEK
     EIKILTDKLK EAETSAEFAE RSVAKLEKTI DDLEDKLKRT KEEHLCTQRM LDQTLLDLND
     M
//