ID A0A2I2ZWN5_GORGO Unreviewed; 985 AA.
AC A0A2I2ZWN5;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Ankyrin repeat domain 44 {ECO:0000313|Ensembl:ENSGGOP00000051534.1};
GN Name=ANKRD44 {ECO:0000313|Ensembl:ENSGGOP00000051534.1};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000051534.1, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000051534.1, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000051534.1, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000051534.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030017862; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030017863; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030017864; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030017865; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030017866; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030017867; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030017868; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030017869; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030017870; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030017871; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I2ZWN5; -.
DR Ensembl; ENSGGOT00000065865.1; ENSGGOP00000051534.1; ENSGGOG00000014558.3.
DR GeneTree; ENSGT00950000182908; -.
DR OMA; KCFRKFV; -.
DR Proteomes; UP000001519; Chromosome 2B.
DR Bgee; ENSGGOG00000014558; Expressed in liver and 6 other cell types or tissues.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 10.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR24123; ANKYRIN REPEAT-CONTAINING; 1.
DR PANTHER; PTHR24123:SF82; SERINE_THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY ANKYRIN REPEAT SUBUNIT B; 1.
DR Pfam; PF00023; Ank; 5.
DR Pfam; PF12796; Ank_2; 8.
DR Pfam; PF13637; Ank_4; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 27.
DR SUPFAM; SSF48403; Ankyrin repeat; 4.
DR PROSITE; PS50297; ANK_REP_REGION; 20.
DR PROSITE; PS50088; ANK_REPEAT; 23.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000001519};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 32..64
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 65..97
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 98..130
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 131..163
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 164..196
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 197..229
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 230..262
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 263..296
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 297..329
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 330..356
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 363..395
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 396..428
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 429..461
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 523..546
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 558..590
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 591..623
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 625..657
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 661..693
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 694..726
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 727..748
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 763..785
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 830..862
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 933..965
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 985 AA; 106753 MW; 0B925EF246857BAC CRC64;
QPPLVQAIFS GDPEEIRMLI HKTEDVNTLD SEKRTPLHVA AFLGDAEIIE LLILSGARVN
AKDNMWLTPL HRAVASRSEE AVQVLIKHSA DVNARDKNWQ TPLHVAAANK AVKCAEVIIP
LLSSVNVSDR GGRTALHHAA LNGHVEMVNL LLAKGANINA FDKKDRRALH WAAYMGHLDV
VALLINHGAE VTCKDKKGYT PLHAAASNGQ INVVKHLLNL GVEIDEINVY GNTALHIACY
NGQDAVVNEL IDYGANVNQP NNNGFTPLHF AAASTHGALC LELLVNNGAD VNIQSKDGKS
PLHMTAVHGR FTRSQTLIQN GGEIDCVDKD GNTPLHVAAR YGHELLINTL ITSGADTAKC
GIHSMFPLHL AALNAHSDCC RKLLSSGFEI DTPDKFGRTC LHAAAAGGNV ECIKLLQSSG
ADFHKKDKCG RTPLHYAAAN CHFHCIETLV TTGANVNETD DWGRTALHYA AASDMDRNKT
ILGNAHENSE ELERARELKE KEATLCLEFL LQNDANPSIR DKEGYNSIHY AAAYGHRQCL
ELLLERTNSG FEESDSGATK SPLHLAAYNG HHQALEVLLQ SLMDLDIRDE KGRTALDLAA
FKGHTECVEA LINQGASIFV KDNVTKRTPL HASVINGHTL CLRLLLEIAD NPEAVDVKDA
KGQTPLMLAV AYGHIDAVSL LLEKEANVDT VDILGCTALH RGIMTGHEEC VQMLLEQEVS
ILCKDSRGRT PLHYAAARGH ATWLSELLQM ALSEEDCCFK DNQGYTPLHW ACYNGNENCI
EVLLEQKCFR KFIGNPFTPL HCAIINDHGN CASLLLGAID SSIVSCRDDK GRTPLHAAAF
ADHVECLQLL LRHSAPVNAV DNSGKTALMM AAENGQAGAV DILVNSAQAD LTVKDKDLNT
PLHLACSKGH EKCALLILDK IQDESLINAK NNALQTPLHV AARNGLKVVV EELLAKGACV
FAVDENASRS NGPRSTPGTA VQKEE
//
