ID A0A2I2ZWR4_GORGO Unreviewed; 390 AA.
AC A0A2I2ZWR4;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Protein prenyltransferase alpha subunit repeat containing 1 {ECO:0000313|Ensembl:ENSGGOP00000051565.1};
GN Name=PTAR1 {ECO:0000313|Ensembl:ENSGGOP00000051565.1};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000051565.1, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000051565.1, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000051565.1, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000051565.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein prenyltransferase subunit alpha
CC family. {ECO:0000256|ARBA:ARBA00006734}.
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DR EMBL; CABD030064195; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030064196; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_018888623.1; XM_019033078.1.
DR AlphaFoldDB; A0A2I2ZWR4; -.
DR Ensembl; ENSGGOT00000058840.1; ENSGGOP00000051565.1; ENSGGOG00000008891.3.
DR GeneTree; ENSGT00390000017892; -.
DR Proteomes; UP000001519; Chromosome 9.
DR Bgee; ENSGGOG00000008891; Expressed in testis and 5 other cell types or tissues.
DR GO; GO:0008318; F:protein prenyltransferase activity; IEA:InterPro.
DR Gene3D; 1.25.40.120; Protein prenylyltransferase; 1.
DR InterPro; IPR002088; Prenyl_trans_a.
DR PANTHER; PTHR11129; PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT; 1.
DR PANTHER; PTHR11129:SF3; PROTEIN PRENYLTRANSFERASE ALPHA SUBUNIT REPEAT-CONTAINING PROTEIN 1; 1.
DR Pfam; PF01239; PPTA; 4.
DR SUPFAM; SSF48439; Protein prenylyltransferase; 1.
DR PROSITE; PS51147; PFTA; 3.
PE 3: Inferred from homology;
KW Prenyltransferase {ECO:0000256|ARBA:ARBA00022602};
KW Reference proteome {ECO:0000313|Proteomes:UP000001519};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022602}.
FT REGION 251..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 390 AA; 45104 MW; 2C23A54650B9B42A CRC64;
MNCEHHLEAS EWIPIVKDEI GLIPCPEARY NRSPIVLVEN KLGVESWCVK FLLPYVHNKL
LLYRTRKQWL NRDELIDVTC TLLLLNPDFT TAWNVRKELI LSGTLNPIKD LHLGKLALTK
FPKSPETWIH RRWVLQQLIQ ETSLPSFVTK GNLGTIPTER AQRLIQEEME VCGEAAGRYP
SNYNAWSHRI WVLQHLAKLD VKILLDELSS TKHWASMHVS DHSGFHYRQF LLKSLISQTV
IDSSVMEQNP LRSEPALVPP KDEEASVSAE EPRINLPHLL EEEVEFSTDL IDSYPGHETL
WCHRRHIFYL QHHLNAGSQL SQAMEVDGLN DSSKQGYSQE TKRLKRTPVP DSLGLEMEHR
FIDQVLSTCR NVEQARFASA YRKWLVTLSQ
//
