ID A0A2I2ZZ11_GORGO Unreviewed; 389 AA.
AC A0A2I2ZZ11;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Schlafen family member 5 {ECO:0000313|Ensembl:ENSGGOP00000052319.1};
GN Name=SLFN5 {ECO:0000313|Ensembl:ENSGGOP00000052319.1};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000052319.1, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000052319.1, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000052319.1, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000052319.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030038300; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_018884071.1; XM_019028526.1.
DR AlphaFoldDB; A0A2I2ZZ11; -.
DR Ensembl; ENSGGOT00000047734.1; ENSGGOP00000052319.1; ENSGGOG00000011259.3.
DR GeneTree; ENSGT00410000025651; -.
DR Proteomes; UP000001519; Chromosome 5.
DR Bgee; ENSGGOG00000011259; Expressed in heart and 6 other cell types or tissues.
DR Gene3D; 3.30.950.30; Schlafen, AAA domain; 1.
DR InterPro; IPR031450; Poxin-SLFN/SLFN_N.
DR InterPro; IPR029684; Schlafen.
DR InterPro; IPR007421; Schlafen_AlbA_2_dom.
DR InterPro; IPR038461; Schlafen_AlbA_2_dom_sf.
DR PANTHER; PTHR12155; SCHLAFEN; 1.
DR PANTHER; PTHR12155:SF26; SCHLAFEN FAMILY MEMBER 5; 1.
DR Pfam; PF17057; B3R; 1.
DR Pfam; PF04326; SLFN_AlbA_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001519}.
FT DOMAIN 80..188
FT /note="Poxin-Schlafen/Schlafen-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF17057"
FT DOMAIN 191..305
FT /note="Schlafen AlbA-2"
FT /evidence="ECO:0000259|Pfam:PF04326"
SQ SEQUENCE 389 AA; 43865 MW; BCA29B3D220858B6 CRC64;
MSLRIDVDTN FPECVVDAGK VTLGTQQRQE MDPRLREKQN EIILRAVCAL LNSGGGIIKA
EIENKGYNYE RHGVGLDVPP IFRSHLDKMQ KENHFLIFVK SWNTEAGVPL ATLCSNLYHR
ERTSTDVMDS QEALAFLKCR TQTPTNINVS NSLGPQAAQG SVQYEGNINV SAAALFDRKQ
LQYLEKLNLP ESTHVEFVMF STDVSHCVKD RLPKCVSAFA NTEGGYVFFG VHDETCQVIG
CEKEKIDLTS LRASIDGCIK KLPVHHFCTQ RPEIKYVLNF LEVHDKGALR GYVCAIKVEK
FCCAVFAKVP SSWQVKDNRV RQLPTREWTA WMMEADPDLS RCPEMVLELS LSSATPRSKP
VCIHKNSECL KEQQKRYFPV SARKTSASQ
//
