ID A0A2I3BPS0_MOUSE Unreviewed; 110 AA.
AC A0A2I3BPS0;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Calcium channel, voltage-dependent, R type, alpha 1E subunit {ECO:0000313|Ensembl:ENSMUSP00000153897.2};
DE Flags: Fragment;
GN Name=Cacna1e {ECO:0000313|Ensembl:ENSMUSP00000153897.2,
GN ECO:0000313|MGI:MGI:106217};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000153897.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000153897.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000153897.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000153897.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000153897.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2I3BPS0; -.
DR SMR; A0A2I3BPS0; -.
DR ProteomicsDB; 314657; -.
DR Antibodypedia; 34433; 143 antibodies from 20 providers.
DR Ensembl; ENSMUST00000226546.2; ENSMUSP00000153897.2; ENSMUSG00000004110.18.
DR AGR; MGI:106217; -.
DR MGI; MGI:106217; Cacna1e.
DR VEuPathDB; HostDB:ENSMUSG00000004110; -.
DR GeneTree; ENSGT00940000155601; -.
DR Proteomes; UP000000589; Chromosome 1.
DR Bgee; ENSMUSG00000004110; Expressed in habenula and 133 other cell types or tissues.
DR ExpressionAtlas; A0A2I3BPS0; baseline and differential.
DR GO; GO:0034702; C:monoatomic ion channel complex; IEA:UniProtKB-KW.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR031649; GPHH_dom.
DR PANTHER; PTHR45628; VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1; 1.
DR PANTHER; PTHR45628:SF5; VOLTAGE-DEPENDENT R-TYPE CALCIUM CHANNEL SUBUNIT ALPHA-1E; 1.
DR Pfam; PF16905; GPHH; 1.
PE 1: Evidence at protein level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Proteomics identification {ECO:0007829|MaxQB:A0A2I3BPS0,
KW ECO:0007829|PeptideAtlas:A0A2I3BPS0};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT DOMAIN 30..83
FT /note="Voltage-dependent L-type calcium channel IQ-
FT associated"
FT /evidence="ECO:0000259|Pfam:PF16905"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000153897.2"
FT NON_TER 110
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000153897.2"
SQ SEQUENCE 110 AA; 12605 MW; 85A2325A8FD68C6A CRC64;
MLNLFVAVIM DNFEYLTRDS SILGPHHLDE FVRVWAEYDR AACGRIPYKD MYKLVRVISP
PLGLGENCPY RVACKRLVLM NMPVAEDMTV HFTSTLMALI RTALDIKIAK
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