ID A0A2I3FRM7_NOMLE Unreviewed; 449 AA.
AC A0A2I3FRM7;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSNLEP00000024738.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000024738.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000024738.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000024738.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the DMRT family.
CC {ECO:0000256|ARBA:ARBA00006834}.
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DR EMBL; ADFV01185217; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01185218; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3FRM7; -.
DR STRING; 61853.ENSNLEP00000024738; -.
DR Ensembl; ENSNLET00000039609.1; ENSNLEP00000024738.1; ENSNLEG00000027959.1.
DR GeneTree; ENSGT00940000161649; -.
DR InParanoid; A0A2I3FRM7; -.
DR OMA; AYPLGTH; -.
DR Proteomes; UP000001073; Chromosome 12.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:0021796; P:cerebral cortex regionalization; IEA:Ensembl.
DR GO; GO:0071542; P:dopaminergic neuron differentiation; IEA:Ensembl.
DR GO; GO:0007405; P:neuroblast proliferation; IEA:Ensembl.
DR GO; GO:0048665; P:neuron fate specification; IEA:Ensembl.
DR GO; GO:0002052; P:positive regulation of neuroblast proliferation; IEA:Ensembl.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
DR GO; GO:0048866; P:stem cell fate specification; IEA:Ensembl.
DR CDD; cd14418; CUE_DMA_DMRTA2; 1.
DR InterPro; IPR005173; DMA.
DR InterPro; IPR026607; DMRT.
DR InterPro; IPR046472; DMRT5_1_DMB_dom.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR12322; DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT; 1.
DR PANTHER; PTHR12322:SF76; DOUBLESEX- AND MAB-3-RELATED TRANSCRIPTION FACTOR A2; 1.
DR Pfam; PF03474; DMA; 1.
DR Pfam; PF20624; DMRT5_DMB; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001073}.
FT DOMAIN 225..261
FT /note="DMA"
FT /evidence="ECO:0000259|Pfam:PF03474"
FT DOMAIN 341..421
FT /note="DMRT5/1 DMB"
FT /evidence="ECO:0000259|Pfam:PF20624"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 56..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 108..227
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 301..324
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 63..77
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..128
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..155
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 449 AA; 43922 MW; 13431F6BBDEF46D1 CRC64;
MELRSELPSV PGAATAAAAT ATGPPVASVA SVAAAAAAAA SLPVSVAGGS PVVRAVGAQS
GRNARAKRKR GTGRKLRSKG PRCCDRSLLA NCSSRHAKLQ KFDLFPKTLL QAGRPGSPPP
PPVKPLSPDG ADSGPGTSSP EVRPGSGSEN GDGESFSGSP LARASKEAGG SCPGSAGPGG
GGGGDEDSPG SASPLGSESG SEADKEEGEA APAPGLGGGS GPRQRTPLDI LTRVFPGHRR
GVLELVLQGC GGDVVQAIEQ VLNHHRGGLA AGLGPAAPPD KAAVGAAAAA DDAWPSRVDA
AAATAGPGLP APLQAGPAAP PHHRPLLAGA MAPGALGSLS SRSAFSPLQP NAGHFGADAG
AYPLGAPLGL SPLRLAYSAA AAHSRGLAFM APYSTAGLVP TLGFRPPMDY AFSDLMRDRS
AAAAAAVHKE PTYGGGLYGP MVNGAPEKQ
//
