ID A0A2I3FUG1_NOMLE Unreviewed; 383 AA.
AC A0A2I3FUG1;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=SRY-box transcription factor 5 {ECO:0000313|Ensembl:ENSNLEP00000025050.1};
GN Name=SOX5 {ECO:0000313|Ensembl:ENSNLEP00000025050.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000025050.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000025050.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000025050.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; ADFV01029324; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01029325; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01029326; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01029327; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01029328; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01029329; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01029330; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01029331; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3FUG1; -.
DR Ensembl; ENSNLET00000042043.1; ENSNLEP00000025050.1; ENSNLEG00000005036.2.
DR GeneTree; ENSGT00940000156122; -.
DR Proteomes; UP000001073; Chromosome 23.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd22030; HMG-box_SoxD; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR PANTHER; PTHR45789; FI18025P1; 1.
DR PANTHER; PTHR45789:SF3; TRANSCRIPTION FACTOR SOX-5; 1.
DR Pfam; PF00505; HMG_box; 1.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; HMG-box; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00267}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073}.
FT DOMAIN 176..244
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 176..244
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 1..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 334..383
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 73..134
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 17..38
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 351..370
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 383 AA; 42582 MW; BFF91E9653FA4C75 CRC64;
RLLGPIPIDE VAQPLNLSAK PKTSDGKSPT SPTSPHMPAL RINSGAGPLK ASVPAALASP
SARVSTIGYL NDHDAVTKAI QEARQMKEQL RREQQVLDGK VAVVNSLGLN NCRTEKEKTT
LESLTQQLAV KQNEEGKFSH AMMDFNLSGD SDGSAGVSES RIYRESRGRG SNEPHIKRPM
NAFMVWAKDE RRKILQAFPD MHNSNISKIL GSRWKAMTNL EKQPYYEEQA RLSKQHLEKY
PDYKYKPRPK RTCLVDGKKL RIGEYKAIMR NRRQEMRQYF NVGQQAQIPI ATAGVVYPGA
IAMAGMPSPH LPSEHSSVSS SPEPGMPVIQ STYGVKGEEP HIKEEIQAED INGEIYDEYD
EEEDDPDVDY GSDSENHIAG QAN
//
