ID A0A2I3FYG9_NOMLE Unreviewed; 433 AA.
AC A0A2I3FYG9;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Divergent protein kinase domain 2B {ECO:0000313|Ensembl:ENSNLEP00000025573.1};
GN Name=DIPK2B {ECO:0000313|Ensembl:ENSNLEP00000025573.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000025573.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000025573.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000025573.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the DIPK family.
CC {ECO:0000256|ARBA:ARBA00006338}.
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DR EMBL; ADFV01063324; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003271074.1; XM_003271026.2.
DR AlphaFoldDB; A0A2I3FYG9; -.
DR STRING; 61853.ENSNLEP00000025573; -.
DR Ensembl; ENSNLET00000056741.1; ENSNLEP00000025573.1; ENSNLEG00000036003.1.
DR GeneID; 100592564; -.
DR KEGG; nle:100592564; -.
DR CTD; 79742; -.
DR GeneTree; ENSGT00520000055625; -.
DR InParanoid; A0A2I3FYG9; -.
DR OMA; TQRFQKW; -.
DR OrthoDB; 2919302at2759; -.
DR Proteomes; UP000001073; Chromosome X.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR InterPro; IPR020519; DIPK2A/B.
DR InterPro; IPR022049; FAM69_kinase_dom.
DR PANTHER; PTHR32073:SF8; DIVERGENT PROTEIN KINASE DOMAIN 2B; 1.
DR PANTHER; PTHR32073; GH11358P; 1.
DR Pfam; PF12260; PIP49_C; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..433
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014117184"
FT DOMAIN 211..389
FT /note="FAM69 protein-kinase"
FT /evidence="ECO:0000259|Pfam:PF12260"
SQ SEQUENCE 433 AA; 48492 MW; C90771549E3A7670 CRC64;
MEPQLGPEAA ALRPGWLALL LWVSALSCSF SLPASSLSSL VPQVRTSYNF GRTFLSLDKC
NACIGTSICK KFFKEEIRSD NWLASHLGLP PDFLLSYPAN YSDDSKIWRP VEIFRLVSKY
QNEISDRRIC ASASAPKTCS IERVLRKTER FQKWLQAKRL TPDLVQGLAS PLLRCPSQRL
LDRVVRRYAE VADAGSIFMD HFTDRDKLRL LYTLAVNSHP ILLQIFPGAE GWPLPKYLGS
CGRFLVSTST RPLQEFYDAP PDQAADLAYQ LLGVLESLRS NDLNYLFYFT HIDAGMFGVF
NNGRLFIRDA SAVGVIDKQE GSQEATGAGE NKDIFSCLVS GCQAQLPSCE SISEKQSLVL
VCQKLLPRLL QGRFPSPVQD DIDSVLAQCG DSTRPDPEVL GAASRLKDIL RPLRTCDSRF
AYRYPDCKYN DKF
//
