ID A0A2I3G0Z7_NOMLE Unreviewed; 207 AA.
AC A0A2I3G0Z7;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Metaxin 2 {ECO:0000313|Ensembl:ENSNLEP00000025897.1};
GN Name=MTX2 {ECO:0000313|Ensembl:ENSNLEP00000025897.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000025897.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000025897.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000025897.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
CC Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00004294}.
CC -!- SIMILARITY: Belongs to the metaxin family.
CC {ECO:0000256|ARBA:ARBA00009170}.
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DR EMBL; ADFV01058807; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01058808; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01058809; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3G0Z7; -.
DR Ensembl; ENSNLET00000036779.1; ENSNLEP00000025897.1; ENSNLEG00000006020.3.
DR GeneTree; ENSGT00950000182919; -.
DR Proteomes; UP000001073; Chromosome 22a.
DR GO; GO:0001401; C:SAM complex; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd03211; GST_C_Metaxin2; 1.
DR Gene3D; 1.20.1050.10; -; 1.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR040079; Glutathione_S-Trfase.
DR InterPro; IPR033468; Metaxin_GST.
DR InterPro; IPR019564; Sam37/metaxin_N.
DR PANTHER; PTHR12289; METAXIN RELATED; 1.
DR PANTHER; PTHR12289:SF38; METAXIN-2; 1.
DR Pfam; PF17171; GST_C_6; 1.
DR Pfam; PF10568; Tom37; 1.
DR SFLD; SFLDS00019; Glutathione_Transferase_(cytos; 1.
DR SFLD; SFLDG01180; SUF1; 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 13..105
FT /note="Mitochondrial outer membrane transport complex
FT Sam37/metaxin N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10568"
FT DOMAIN 131..193
FT /note="Metaxin glutathione S-transferase"
FT /evidence="ECO:0000259|Pfam:PF17171"
SQ SEQUENCE 207 AA; 23619 MW; 4834908DCACFE233 CRC64;
MSLVAEAFVS QIAGKVPFIH VGNQVVSELG PIVQFVKAKG HSLSDGLDEV QKAEMKAYME
LVNNMLLTAE LYLQWCDEAT VGEITHARYG SPYPWPLNHI LAYQKQWEVK RKMKAIGWGK
KTLDQVLEDV DQCCQALSQR LGTQSYFFNK QPTELDALVF GHLYTILTTQ LTNDELSEKV
KNYSNLLAFC RRIEQHYFED RGKGRLS
//
