ID   A0A2I3G2A8_NOMLE        Unreviewed;       384 AA.
AC   A0A2I3G2A8;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Dishevelled segment polarity protein 1 {ECO:0000313|Ensembl:ENSNLEP00000026283.1};
GN   Name=DVL1 {ECO:0000313|Ensembl:ENSNLEP00000026283.1};
OS   Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC   Nomascus.
OX   NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000026283.1, ECO:0000313|Proteomes:UP000001073};
RN   [1] {ECO:0000313|Ensembl:ENSNLEP00000026283.1, ECO:0000313|Proteomes:UP000001073}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Gibbon Genome Sequencing Consortium;
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSNLEP00000026283.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; ADFV01120213; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01120214; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01120215; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01120216; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A2I3G2A8; -.
DR   Ensembl; ENSNLET00000056594.1; ENSNLEP00000026283.1; ENSNLEG00000000028.2.
DR   GeneTree; ENSGT00950000182903; -.
DR   Proteomes; UP000001073; Chromosome 24.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0022603; P:regulation of anatomical structure morphogenesis; IEA:UniProt.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.240.130; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000591; DEP_dom.
DR   InterPro; IPR024580; Dishevelled_C-dom.
DR   InterPro; IPR003351; Dishevelled_protein_dom.
DR   InterPro; IPR001158; DIX.
DR   InterPro; IPR038207; DIX_dom_sf.
DR   InterPro; IPR015506; Dsh/Dvl-rel.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR10878; SEGMENT POLARITY PROTEIN DISHEVELLED; 1.
DR   PANTHER; PTHR10878:SF5; SEGMENT POLARITY PROTEIN DISHEVELLED HOMOLOG DVL-1-RELATED; 1.
DR   Pfam; PF02377; Dishevelled; 1.
DR   Pfam; PF00778; DIX; 1.
DR   Pfam; PF12316; Dsh_C; 1.
DR   SMART; SM00021; DAX; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50186; DEP; 1.
DR   PROSITE; PS50841; DIX; 1.
PE   4: Predicted;
KW   Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW   Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687, ECO:0000256|PROSITE-
KW   ProRule:PRU00069}.
FT   DOMAIN          1..85
FT                   /note="DIX"
FT                   /evidence="ECO:0000259|PROSITE:PS50841"
FT   DOMAIN          211..236
FT                   /note="DEP"
FT                   /evidence="ECO:0000259|PROSITE:PS50186"
FT   REGION          76..204
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        107..124
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        125..160
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        164..199
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   384 AA;  41667 MW;  36220EF71479E229 CRC64;
     MAETKIIYHM DEEETPYLVK LPVAPERVTL ADFKNVLSNR PVHAYKFFFK SMDQDFGSVG
     REACASLLVL AEGAHSDVGS QGTDSHTDLP PPLERTGGIG DSRPPSFHPN VASSRDGMDN
     ETGTESMVSH RRERARRRNR EEAARTNGHP RGDRRRDVGL PPDSASTALS SELESSSFVD
     SDEDGSTSRL SSSTEQSTSS RLIRKHKRRS LLKHGFLRHT VNKITFSEQC YYVFGDLCSN
     LATLNLNSGS SGASDQDTLA PLPHPAAPWP LGQGYPYQYP GPPPCFPPAY QDPGFSYGSG
     STGSQQSEGK NAAPTCPSLA PCRNRMASCT HTADPSGHTG GSCWGLQVQA LPGELGGTQL
     QLQPGRPSRY QEVCPGWCLF PMVL
//