ID A0A2I3G985_NOMLE Unreviewed; 285 AA.
AC A0A2I3G985;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=MAX interactor 1, dimerization protein {ECO:0000313|Ensembl:ENSNLEP00000027876.1};
GN Name=MXI1 {ECO:0000313|Ensembl:ENSNLEP00000027876.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000027876.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000027876.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000027876.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; ADFV01163971; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01163972; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01163973; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01163974; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01163975; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01163976; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01163977; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01163978; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01163979; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3G985; -.
DR Ensembl; ENSNLET00000048134.1; ENSNLEP00000027876.1; ENSNLEG00000015457.3.
DR GeneTree; ENSGT00940000155809; -.
DR Proteomes; UP000001073; Chromosome 3.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR PANTHER; PTHR11969; MAX DIMERIZATION, MAD; 1.
DR PANTHER; PTHR11969:SF13; MAX-INTERACTING PROTEIN 1; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073}.
FT DOMAIN 124..176
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 96..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 218..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 166..196
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 21..43
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 121..135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..244
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 245..285
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 285 AA; 31626 MW; 846818DC7DF6F580 CRC64;
MGKRGRPRKE ARCEGAGLAP AAPPAVPPAA TAPQPPALPE EPAGAKPRCP FSDIFNTSEN
SMEKHINTFL QNVQILLEAA SYLEQIEKEN KKCEHGYASS FPSMPSPRLQ HSKPPRRLSR
AQKHSSGSSN TSTANRRAHL RLCLERLKVL IPLGPDCTRH TTLGLLNKAK AHIKKLEEAE
RKSQHQLENL EREQRFLKWR LEQLQGPQEM ERIRMDSIGS TISSDRSDSE REEIEVDVES
TEFSHGEVDN ISTTSISDID DHSSLPSIGS DEGYSSASVK LSFTS
//
