ID A0A2I3GAL9_NOMLE Unreviewed; 1228 AA.
AC A0A2I3GAL9;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Atrophin 1 {ECO:0000313|Ensembl:ENSNLEP00000028335.1};
GN Name=ATN1 {ECO:0000313|Ensembl:ENSNLEP00000028335.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000028335.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000028335.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000028335.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ADFV01078518; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01078519; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01078520; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3GAL9; -.
DR STRING; 61853.ENSNLEP00000028335; -.
DR Ensembl; ENSNLET00000033100.1; ENSNLEP00000028335.1; ENSNLEG00000032638.1.
DR GeneTree; ENSGT00940000153615; -.
DR InParanoid; A0A2I3GAL9; -.
DR OMA; YPHSLES; -.
DR Proteomes; UP000001073; Chromosome 23.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0016363; C:nuclear matrix; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0019904; F:protein domain specific binding; IEA:Ensembl.
DR GO; GO:0003713; F:transcription coactivator activity; IEA:Ensembl.
DR GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR GO; GO:0001906; P:cell killing; IEA:Ensembl.
DR GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR GO; GO:0008340; P:determination of adult lifespan; IEA:Ensembl.
DR GO; GO:0030011; P:maintenance of cell polarity; IEA:Ensembl.
DR GO; GO:0008584; P:male gonad development; IEA:Ensembl.
DR GO; GO:0035264; P:multicellular organism growth; IEA:Ensembl.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR GO; GO:0051402; P:neuron apoptotic process; IEA:Ensembl.
DR GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
DR GO; GO:0032094; P:response to food; IEA:Ensembl.
DR GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR InterPro; IPR017993; Atrophin-1.
DR InterPro; IPR002951; Atrophin-like.
DR InterPro; IPR026317; P_C10.
DR PANTHER; PTHR13859:SF9; ATROPHIN-1; 1.
DR PANTHER; PTHR13859; ATROPHIN-RELATED; 1.
DR Pfam; PF03154; Atrophin-1; 2.
DR Pfam; PF14974; P_C10; 1.
DR PRINTS; PR01222; ATROPHIN.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT REGION 1..597
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 611..756
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 793..819
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..31
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..95
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 109..127
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..155
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..178
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 203..220
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 255..272
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 288..311
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 347..368
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..405
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 415..437
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 460..476
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 542..579
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 580..594
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 672..707
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 725..743
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 793..816
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1228 AA; 128391 MW; A2E6BC0D08750F9B CRC64;
MKTRQNKDSM SMRSGRKKEA PGPREELRSR GRASPGGVST SSSDGKAEKS RQTAKKARVE
EASTPKVNKQ GRSEEISESE SEETNAPKKT KTEQELPRPQ SPSDLDSLDG RSLNDDGSSD
PRDIDQDNRS TSPSIYSPGS VENDSDSSSG LSQGPARPYH QPPLFPPSPP PPDSTPRQPE
AGFEPHPSVT PTGYHAPMEP PTSRMFQAPP GAPPPHPQLY PGGTGGVLSG PPMGSKGGGA
ASSVGGPNGG KQHPPPTTPI SVSSSGASGA PPTKPPTTAV GGGNLPSAPP PANFPHVTPN
LPPPPALRPL NNASASPPGL GAQPLPGHLP SPHAMGQGMG GLPPGPEKGP TLAPSPHSLP
PASSSSAPAP PMRFPYSSSS SSSAAASSSS SSSSSSASPY PASQALPSYP HSFPPPTSLS
VSNQPPKYTQ PSLPSQAVWS QGPPPPPPYG RLLANSSAHP GPFPPSTGAQ STAHAPASTH
HHHHQQQQQQ QHHGSSGPPP PGAFPHPLEG GSSHHAHPYA MSPSLGSLRP YPPGPAHLPP
PHSQVSYSQA GPNGPPVSSS SNSSSSTSQG SYPCSHPSPS QGPQGAPYPF PPVPTVTTSS
ATLSTVIATV ASSPAGYKTA SPPGPPPYGK RALSPGAYKT ATPPGYKPGS PPSFRTGTPP
GYRGTSPPAG PGTFKPGSPT VGPGPLPPAG PSGLPSLPPP PAAPASGPPL SATQIKQEPA
EEYETPESPV PPARSPSPPP KVVDVPSHAS QSARFNKHLD RGFNSCARSD LYFVPLEGSK
LAKKRADLVE KVRREAEQRA REEKERERER EPTSFHNFRF DSTFPCTPQK LAQEGRAPVE
CPSLGPVPHR PPFEPGSAVA TVPPYLGPDT PALRTLSEYA RPHVMSPGNR NHPFYVPLGA
VDPGLLGYNV PALYSSDPAA REREREARER DLRDRLKPGF EVKPSELEPL HGVPGPGLDP
FPRHGGLALQ PGPPGLHPFP FHPSLGPLER ERLALAAGPA LRPDMSYAER LAAERQHAER
VAALGNDPLA RLQMLNVTPH HHQHSHIHSH LHLHQQDAIH AASASVHPLI DPLASGSHLT
RIPYPAGTLP NPLLPHPLHE NEVLRHQLFA APYRDLPASL SAPMSAAHQL QAMHAQSAEL
QRLALEQQQW LHAHHPLHSV PLPAQEDYYS VDPPLPLAGV LKFARLVKSY EAQDPEIASL
SGKLKALFLP PMTLPPHGPA AGGSVAAS
//
