ID A0A2I3GEH3_NOMLE Unreviewed; 976 AA.
AC A0A2I3GEH3;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Ataxin 2 like {ECO:0000313|Ensembl:ENSNLEP00000029673.1};
GN Name=ATXN2L {ECO:0000313|Ensembl:ENSNLEP00000029673.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000029673.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000029673.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000029673.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the ataxin-2 family.
CC {ECO:0000256|ARBA:ARBA00007503}.
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DR EMBL; ADFV01196788; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01196789; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01196790; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3GEH3; -.
DR Ensembl; ENSNLET00000032868.1; ENSNLEP00000029673.1; ENSNLEG00000011004.3.
DR GeneTree; ENSGT00940000157795; -.
DR Proteomes; UP000001073; Chromosome 2.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR InterPro; IPR009818; Ataxin-2_C.
DR InterPro; IPR045117; ATXN2-like.
DR InterPro; IPR009604; LsmAD_domain.
DR InterPro; IPR025852; SM_dom_ATX.
DR PANTHER; PTHR12854; ATAXIN 2-RELATED; 1.
DR PANTHER; PTHR12854:SF8; ATAXIN-2-LIKE PROTEIN; 1.
DR Pfam; PF06741; LsmAD; 1.
DR Pfam; PF07145; PAM2; 1.
DR Pfam; PF14438; SM-ATX; 1.
DR SMART; SM01272; LsmAD; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..976
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014197748"
FT DOMAIN 150..219
FT /note="LsmAD"
FT /evidence="ECO:0000259|SMART:SM01272"
FT REGION 202..595
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 721..750
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 766..841
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 923..945
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 202..218
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 317..336
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 360..382
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 466..484
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 553..595
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 766..819
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 822..836
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 976 AA; 103944 MW; EBD98F5B6B681BF7 CRC64;
MYSGGLWTLF LFFPLCQGST CDVKVKNGTT YEGIFKTLSS KFELAVDAVH RKASEPAGGP
RREDIVDTMV FKPSDVMLVH FRNVDFNYAT KDKFTDSAIA MNSKVNGEHK EKVLQRWEGG
DSNSDDYDLE SDMSNGWDPN EMFKFNEENY GVKTTYDSSL SSYTVPLEKD NSEEFRQREL
RAAQLAREIE SSPQYRLRIA MENDDGRTEE EKHSAVQRQG SGRESPSLAS REGKYIPLPQ
RVREGPRGGV RCSSSRGGRP GLSSLPPRGP HHLDNSSPGP GSEARGINGG PSRMSPKAQR
PLRGAKTLSS PSNRPSGETS VPPPPAAPPF LPVGRMYPPR SPKSAAPAPI SASCPEPPIG
SAVPTSSASI PVTSSVSDPG VGSISPASPK ISLAPTDVKE LSTKEPGRTL EPQELARIAG
KVPGLQNEQK RFQLEELRKF GPGLGSGSDW TLQPSSSPEN SLDPFPPRIL KEEPKGKEKE
VDGLLTSEPM GSPVSSKTES VSDKEDKSPL APAGGTEGPE QPQPPCPSQT GSPPVGLIKG
EDKDEGPVAE QVKKSTLNPN AKEFNPTKPL LSVNKSTSTP TSPGPRTHST PSIPVLTAGQ
SGLYSPQYIS YIPQIHMGPA VQAPQMYPYP VSNSVPGQQG KYRGAKGELP RAYWQRSDQH
QPASAPPMMQ AAAAAGPPLV AATPYSSYIP YNPQQFPGQP AMMQPMAHYP SQPVFAPMLQ
SNPRMLTSGS HPQAIVSSST PQYPSAEQPT PQALYATVHQ SYPHHATQLH AHQPQPATTP
TGSQPQSQHA APSPVQHQAG QAPHLGSGQP QQNLYHPGAL TGTPPSLPPG PSAQSPQSSF
PQPAAVYAIH HQQLPHGFTN MAHVTQAHVQ TGITAAPPPH PGAPHPPQVM LLHPPQSHGG
PPQGAVPQSG VPALSASTPS PYPYIGHPQG EQPGQAPGFP GGADDRIREF SLAGGIWHGR
AEGLQVGQDA RVLGGE
//
