ID A0A2I3GFJ1_NOMLE Unreviewed; 373 AA.
AC A0A2I3GFJ1;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=CXADR like membrane protein {ECO:0000313|Ensembl:ENSNLEP00000030058.1};
GN Name=CLMP {ECO:0000313|Ensembl:ENSNLEP00000030058.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000030058.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000030058.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000030058.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01057396; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01057397; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01057398; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01057399; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01057400; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01057401; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01057402; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01057403; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01057404; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01057405; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003253353.1; XM_003253305.3.
DR AlphaFoldDB; A0A2I3GFJ1; -.
DR Ensembl; ENSNLET00000034792.1; ENSNLEP00000030058.1; ENSNLEG00000007420.2.
DR GeneID; 100580189; -.
DR KEGG; nle:100580189; -.
DR CTD; 79827; -.
DR GeneTree; ENSGT00940000161031; -.
DR OrthoDB; 4605345at2759; -.
DR Proteomes; UP000001073; Chromosome 15.
DR GO; GO:0005881; C:cytoplasmic microtubule; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00096; Ig; 1.
DR CDD; cd20960; IgV_CAR_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR042454; CLMP.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR44783; CXADR-LIKE MEMBRANE PROTEIN; 1.
DR PANTHER; PTHR44783:SF1; CXADR-LIKE MEMBRANE PROTEIN; 1.
DR Pfam; PF13895; Ig_2; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 2.
DR SMART; SM00408; IGc2; 2.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 2.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..373
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014138092"
FT TRANSMEM 231..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 29..116
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 135..224
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 264..373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 264..282
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 285..327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 354..373
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 373 AA; 41296 MW; 27886D14BE82143B CRC64;
MSLLLLLLLV SYYVGTLGTH TEIRRVAEEK VTLPCHHQLG LPEKDTLDIE WLLTDNEGNQ
KVVITYSSRH VYNNLTEEQK GRVAFASNFL AGDASLQIEP LKPSDEGRYT CKVKNSGRYV
WSHVILKVLV RPSKPKCELE GELTEGSDLT LQCESSSGTE PIVYYWQRIR EKEGEDERLP
PKSRIDYNHP GRVLLQNLTM SYSGLYQCTA GNEAGKESCV VRVTVQYVQS IGMVAGAVTG
IVAGALLIFL LVWLLIRRKD KERYEEEERP NEIREDAEAP KARLVKPSSS SSGSRSSRSG
SSSTRSTANS ASRSQRTLST DAAPQPGLAT QAYSLVGPEV RGSEPKKVHH ATLTKAETTP
SMIPSQSRAF QTV
//
