ID A0A2I3GGU1_NOMLE Unreviewed; 517 AA.
AC A0A2I3GGU1;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Taste 1 receptor member 1 {ECO:0000313|Ensembl:ENSNLEP00000030514.1};
GN Name=TAS1R1 {ECO:0000313|Ensembl:ENSNLEP00000030514.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000030514.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000030514.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000030514.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; ADFV01080151; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01080152; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01080153; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01080154; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3GGU1; -.
DR Ensembl; ENSNLET00000052073.1; ENSNLEP00000030514.1; ENSNLEG00000008554.3.
DR GeneTree; ENSGT00940000161264; -.
DR Proteomes; UP000001073; Chromosome 24.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR PANTHER; PTHR24061:SF3; TASTE RECEPTOR TYPE 1 MEMBER 1; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..517
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014153272"
FT TRANSMEM 244..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 280..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 311..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..425
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 437..459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 465..485
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 242..507
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 517 AA; 57717 MW; 07F7A332DE882451 CRC64;
MLLCTARLVG LQLLISWCWA FACHSTESSP DFTLPGDYLL AGLFPLHSGC LQVRHRPEVT
LCDSGAILAH CKLRLPGSHH SPASASRVAE TTGARHHAQL IFFVFLLLEQ IYKVNFLLHK
DTVMFDDNRD PLSSYNIIAW DWNGPKWTFT VLGSSTWSPV QLNINETKIQ WHGKNNQVPK
SVCSSDCLEG YQRVVMGFHH CCFECVGEWA MEQPCGKEEW APEGSQTCFL RTVAFLAWHE
HTSWVLLAAN TVLLLLLLGT AGLFAWHLDT PVVRSAGGRL CFLMLGSLAA GSGSLYGFFG
EPTRPACLLR QALFALGFTI FLSCLTVRSF QLIIIFKFST KVPTFYHAWV QNHGAGLFVM
ISSAAQLLIC LTWLVVWTPL PTREYQRFPH LVMLECTEAN SLGFILAFLY NGLLSISAFA
CSYLGKDLPE NYNEAKCVTF SLLFNFVSWI AFFTTASVYD GKYLPAVNMM AGLSSLSSGF
GGYFLPKCYV ILCRPDLNST EHFQASIQDY TRRCGST
//
