ID A0A2I3GK98_NOMLE Unreviewed; 1141 AA.
AC A0A2I3GK98;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Fibronectin type III domain containing 3A {ECO:0000313|Ensembl:ENSNLEP00000031682.1};
GN Name=FNDC3A {ECO:0000313|Ensembl:ENSNLEP00000031682.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000031682.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000031682.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000031682.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01053503; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01053504; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01053505; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01053506; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01053507; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01053508; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01053509; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01053510; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01053511; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01053512; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3GK98; -.
DR Ensembl; ENSNLET00000056361.1; ENSNLEP00000031682.1; ENSNLEG00000003383.2.
DR GeneTree; ENSGT00940000159319; -.
DR Proteomes; UP000001073; Chromosome 5.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 9.
DR Gene3D; 2.60.40.10; Immunoglobulins; 9.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR24099; E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED; 1.
DR PANTHER; PTHR24099:SF9; FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN 3A; 1.
DR Pfam; PF00041; fn3; 7.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 9.
DR SUPFAM; SSF49265; Fibronectin type III; 6.
DR PROSITE; PS50853; FN3; 9.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1117..1140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 211..312
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 316..408
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 412..505
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 509..603
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 607..700
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 704..794
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 804..893
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 894..988
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 989..1094
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 103..191
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 111..141
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 162..177
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1141 AA; 125746 MW; DE93685D6F1C0E3C CRC64;
MGPAQVPMMS PNGSVPPIYV PPGYAPQVIE DNGVRRVVVV PQAPEFHPGG HTVLHRSPHP
PLPGFIPVPT MMPPPPRHMY SPVTGAGDMT TQYMPQYQSS QVYGDVDAHS THGRSNFRDE
RSSKTYERLQ KKLKDRQGTQ KDKMSSPPSS PQKCPSPINE HNGLIKGQNT GGINTGSAKI
KSGKGKGGTQ VDTEIEEKDE ETKAFEALLS NIVKPVASDI QARTVVLTWS PPSSLINGET
DESTVPELYG YEVLISSTGK DGKYKSVYVG EETNITLNDL KPATDYHAKV QAEYNSIKGT
PSEAEIFTTL SCEPDTPNPP RIANRTKNSL TLQWKAPSDN GSKIQNFVLE WDEGKGNGEF
YQCYMGSQKQ FKITKLSPAM GCKFRLSARN DYGTSGFSEE VLYYTSGCAP SMPASPVLTK
AGITWLSLQW SKPSGTPSDE GISYILEMEE ETSGYGFKPK YDGEDLAYTV KNLRRSTKYK
FKVIAYNSEG KSNPSEVVEF TTCPDKPGIP VKPSVKGKIH SHSFKITWDP PKDNGGAAIN
KYVVEMAEGS NGNKWEMIYS GATREHLCDR LNPGCFYRLR VYCISDGGQS AVSESLLVQT
PAVPPGPCLP PRLQGRPKAK EIQLRWGPPL VDGGSPISCY SVEMSPIEKD EPREVYQGSE
VECTVSSLLP GKTYSFRLHA ANKMGFGPFS EKCDITTAPG PPDQCKPPQV TCRSATCAQV
NWEVPLSNGT DVTEYRLEWG GVEGSMQICY CGPGLNYEIK GLSPATTYYC RVQALSVVGA
GPFSEVVACV TPPSVPGIVT CLQEISDDEI ENPHYSPSTC LAISWEKPCD HGSEILAYSI
DFGDKQSLTV GKVTSYIINN LQPDTTYRIR IQALNSLGAG PFSHMIKLKT KPLPPDPPRL
ECVAFSHQNL KLKWGEGTPK TLSTDSIQYH LQMEDKNGRF VSLYRGPCHT YKVQRLNEST
SYKFCIQACN EAGEGPLSQE YIFTTPKSVP AALKAPKIEK VNDHICEITW ECLQPMKGDP
VIYSLQVMLG KDSEFKQIYK GPDSSFRYSS LQLNCEYRFR VCAIRQCQDS LGHQDLVGPY
STTVLFISQR TEPPASTNRD TVESTRTRRA LSDEQCAAVI LVLFAFFSIL IAFIIQYFVI
K
//
