ID A0A2I3GMF3_NOMLE Unreviewed; 127 AA.
AC A0A2I3GMF3;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Calcitonin related polypeptide beta {ECO:0000313|Ensembl:ENSNLEP00000032489.1};
GN Name=CALCB {ECO:0000313|Ensembl:ENSNLEP00000032489.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000032489.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000032489.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000032489.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the calcitonin family.
CC {ECO:0000256|ARBA:ARBA00009222}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ADFV01112485; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003254310.1; XM_003254262.2.
DR RefSeq; XP_004090718.1; XM_004090670.2.
DR AlphaFoldDB; A0A2I3GMF3; -.
DR STRING; 61853.ENSNLEP00000032489; -.
DR Ensembl; ENSNLET00000058576.1; ENSNLEP00000032489.1; ENSNLEG00000017711.3.
DR GeneID; 100594283; -.
DR KEGG; nle:100594283; -.
DR GeneTree; ENSGT00940000156267; -.
DR InParanoid; A0A2I3GMF3; -.
DR OMA; TATCATH; -.
DR OrthoDB; 3910643at2759; -.
DR Proteomes; UP000001073; Chromosome 15.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR Gene3D; 6.10.250.2190; -; 1.
DR InterPro; IPR021117; Calcitonin-like.
DR InterPro; IPR021116; Calcitonin/adrenomedullin.
DR InterPro; IPR018360; Calcitonin_CS.
DR InterPro; IPR015476; Calcitonin_gene-rel_peptide.
DR InterPro; IPR001693; Calcitonin_peptide-like.
DR PANTHER; PTHR10505:SF3; CALCITONIN GENE-RELATED PEPTIDE 2; 1.
DR PANTHER; PTHR10505; CALCITONIN-RELATED; 1.
DR Pfam; PF00214; Calc_CGRP_IAPP; 1.
DR PRINTS; PR00817; CALCITONINB.
DR SMART; SM00113; CALCITONIN; 1.
DR PROSITE; PS00258; CALCITONIN; 1.
PE 3: Inferred from homology;
KW Amidation {ECO:0000256|ARBA:ARBA00022815};
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR621116-50};
KW Hormone {ECO:0000256|ARBA:ARBA00022702};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..127
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014162997"
FT DOMAIN 80..122
FT /note="Calcitonin peptide-like"
FT /evidence="ECO:0000259|SMART:SM00113"
FT DISULFID 83..88
FT /evidence="ECO:0000256|PIRSR:PIRSR621116-50"
SQ SEQUENCE 127 AA; 13680 MW; AD76F1B26C9A19A7 CRC64;
MGFRKFSPFL ALSILVLYQA GGLQAAPFRS ALESSADPAT LSKEDARLLL AALVQDYVQM
KASELKQEQE TQGSSSTAQK RACNTATCVT HRLAGLLSRS GGMVKSNFVP TNVGSKAFGR
RRRDLQA
//
