ID   A0A2I3GNE4_NOMLE        Unreviewed;       459 AA.
AC   A0A2I3GNE4;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Protein-glucosylgalactosylhydroxylysine glucosidase {ECO:0000313|Ensembl:ENSNLEP00000032844.1};
GN   Name=PGGHG {ECO:0000313|Ensembl:ENSNLEP00000032844.1};
OS   Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC   Nomascus.
OX   NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000032844.1, ECO:0000313|Proteomes:UP000001073};
RN   [1] {ECO:0000313|Ensembl:ENSNLEP00000032844.1, ECO:0000313|Proteomes:UP000001073}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Gibbon Genome Sequencing Consortium;
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSNLEP00000032844.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 65 family.
CC       {ECO:0000256|ARBA:ARBA00006768}.
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DR   EMBL; ADFV01129350; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01129351; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A2I3GNE4; -.
DR   Ensembl; ENSNLET00000048210.1; ENSNLEP00000032844.1; ENSNLEG00000008207.3.
DR   GeneTree; ENSGT00390000006297; -.
DR   Proteomes; UP000001073; Chromosome 21.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 1.50.10.10; -; 2.
DR   InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR   InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR   InterPro; IPR005195; Glyco_hydro_65_M.
DR   PANTHER; PTHR11051; GLYCOSYL HYDROLASE-RELATED; 1.
DR   PANTHER; PTHR11051:SF8; PROTEIN-GLUCOSYLGALACTOSYLHYDROXYLYSINE GLUCOSIDASE; 1.
DR   Pfam; PF03632; Glyco_hydro_65m; 1.
DR   SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001073}.
FT   DOMAIN          111..273
FT                   /note="Glycoside hydrolase family 65 central catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF03632"
FT   REGION          331..459
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        347..393
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        423..459
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   459 AA;  49736 MW;  5381E705780A0961 CRC64;
     MLWTPAPPDL TLGEGEEDRT WDFLTAVGSS QAEAQACLTE ALQLQARGAL YTAHTQAWAQ
     LWAECGLDVV GPLPLRQALR GSLYYLLSAL PQPKAPGYIC HGLSPGGLSN GSREECYWGH
     VFWDQDLWMF PNILMFHPEA TRAILEYRIR TLGGALENAQ NLGYQGAKFA WESAGSGLEV
     CPEDIYGAQE VHVNGAVVLA FELYYHTTQD LQLFREAGGW DVVRAVAEFW CSRVEWSPRE
     EELCTEHHLG LVCPGYHSGV NNSVYTNVLV QNRKNLEIYE AVTSPQGPAM TWSMFAVGWM
     ELKDAARAWG LLDRSFANVA EPFKVSLATP ASHWAPRGGS GARLPSHPPA APSPPGCPLT
     PRLPPHSQAA PSPPGCPLTP RLPLTPRLPS HPQAAPHPQA ASLPAGHKVS FPCSAGRIQR
     SPPKPPGSSS SEDPLQSPLW VTLGSSSPTE SLTVDPASE
//