ID A0A2I3GPK0_NOMLE Unreviewed; 168 AA.
AC A0A2I3GPK0;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=TNF receptor superfamily member 19 {ECO:0000313|Ensembl:ENSNLEP00000033241.1};
GN Name=TNFRSF19 {ECO:0000313|Ensembl:ENSNLEP00000033241.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000033241.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000033241.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000033241.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00206}.
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DR EMBL; ADFV01074971; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01074972; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01074973; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01074974; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3GPK0; -.
DR Ensembl; ENSNLET00000053938.1; ENSNLEP00000033241.1; ENSNLEG00000013363.3.
DR GeneTree; ENSGT00940000153259; -.
DR Proteomes; UP000001073; Chromosome 5.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR GO; GO:0043123; P:positive regulation of canonical NF-kappaB signal transduction; IEA:InterPro.
DR GO; GO:0046330; P:positive regulation of JNK cascade; IEA:InterPro.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 1.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR InterPro; IPR047526; TNR19/27/EDAR.
DR PANTHER; PTHR12120; TNFR-CYS DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12120:SF1; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 19; 1.
DR Pfam; PF00020; TNFR_c6; 2.
DR SMART; SM00208; TNFR; 2.
DR PROSITE; PS00652; TNFR_NGFR_1; 1.
DR PROSITE; PS50050; TNFR_NGFR_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00206}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..168
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014122762"
FT DOMAIN 28..72
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 28..72
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 49..62
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
SQ SEQUENCE 168 AA; 19012 MW; F7A7095DCC6D523F CRC64;
MALKVLLEQE KTFFTLLVLL GYLSCKVTCE TGDCRQQEFR DWSGNCVPCN QCGPGMELSK
ECGFGYGEDA QCVTCRLHRF KEDWGFQKCK PCLDCTVVNR FQKANCSATS DAICGDCLPG
VQQKGPHQTP DIGLFILDFP AFRTMRNKFL LFINYPVCDI LLQQHKTD
//
