ID A0A2I3GSG2_NOMLE Unreviewed; 185 AA.
AC A0A2I3GSG2;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
GN Name=ICOSLG {ECO:0000313|Ensembl:ENSNLEP00000034273.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000034273.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000034273.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000034273.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01100729; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01100730; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01100731; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01100732; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004092379.1; XM_004092331.2.
DR AlphaFoldDB; A0A2I3GSG2; -.
DR Ensembl; ENSNLET00000049296.1; ENSNLEP00000034273.1; ENSNLEG00000033148.1.
DR GeneTree; ENSGT00940000161590; -.
DR Proteomes; UP000001073; Chromosome 25.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR24100; BUTYROPHILIN; 1.
DR PANTHER; PTHR24100:SF55; ICOS LIGAND-RELATED; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..185
FT /note="Ig-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014117162"
FT TRANSMEM 137..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 6..110
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 185 AA; 20153 MW; 0B1D9F5A15BD2D6D CRC64;
MRLGSPGLLF LLFSSLRAAN FSVPVVSAPN GPSQDELTFT CTSINGYPRP NVYWINKTDN
SLLDQALQND TVFLNTRGLY DVVSVLRIAW TPSVNIGCCI ENVLLQQNLT VGSQTGNEIG
ERDKITENPV STGEKHVATW SILAVPCLLV AVAVAIFLVL RGRWLQGSYA GVWAVRPEPE
LTGHV
//
