ID A0A2I3GUV6_NOMLE Unreviewed; 515 AA.
AC A0A2I3GUV6;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Nuclear receptor coactivator 4 {ECO:0000313|Ensembl:ENSNLEP00000035163.1};
GN Name=NCOA4 {ECO:0000313|Ensembl:ENSNLEP00000035163.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000035163.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000035163.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000035163.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01105773; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01105774; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01105775; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3GUV6; -.
DR Ensembl; ENSNLET00000032977.1; ENSNLEP00000035163.1; ENSNLEG00000035317.1.
DR GeneTree; ENSGT00390000008403; -.
DR Proteomes; UP000001073; Chromosome 18.
DR GO; GO:0003713; F:transcription coactivator activity; IEA:InterPro.
DR GO; GO:0006879; P:intracellular iron ion homeostasis; IEA:InterPro.
DR InterPro; IPR022174; ARA70.
DR InterPro; IPR039947; NCoA-4.
DR PANTHER; PTHR17085; NUCLEAR RECEPTOR COACTIVATOR 4; 1.
DR PANTHER; PTHR17085:SF5; NUCLEAR RECEPTOR COACTIVATOR 4; 1.
DR Pfam; PF12489; ARA70; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001073}.
FT DOMAIN 99..227
FT /note="Nuclear coactivator"
FT /evidence="ECO:0000259|Pfam:PF12489"
FT REGION 402..425
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 515 AA; 58364 MW; 4D144D4A74DB39A7 CRC64;
MNRWTLFISL KRRHFNSRLS SCTRLGSLTL KPEDSTVLLF EADTTTLRQT ITTFGSLKTI
QIPEHLMAHA SSANIGPFLE KRGYISMPEQ KSASGIVAVP LSECLPGSKP ASGHQAPYIP
STNPQDWLTQ KQTLEKSQTS SRARNFFNNV GGNLKGLENW LLKSEKPSYQ KCNSHSTTSS
FSIEMEKVGD QELPDQDKMD LSDWLVTPQE SHKLRKPENG SRETSEKFKL LFQSYNVNDW
LVKTDSCTNC QGNQPKGVEI ENLGNLKCLN DHLEAKKPLS TPSMVTEDWL VQNHQDPCKV
EEVCRANEPC TSFADCVCDE NCEKEALYKW LLKKEGKDKN GMPVEPKPEP EKHKDSLNVW
LCPSRKEVIE QTKAPKAMTP SRIADSFQVI KNSPLSEWLI RPPYKEGSPK EVPSTEDRAG
KQKFKSPMNT SWCSFNTADW VLPGKKMGNL SQLSSGEDKW LLRKKAQEVL LNSPLQEEHN
FPPDHYGLPA VCDLFACMQL KVDKEKWLYR TPLQM
//
