ID A0A2I3GWS8_NOMLE Unreviewed; 168 AA.
AC A0A2I3GWS8;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Troponin I1, slow skeletal type {ECO:0000313|Ensembl:ENSNLEP00000035697.1};
GN Name=TNNI1 {ECO:0000313|Ensembl:ENSNLEP00000035697.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000035697.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000035697.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000035697.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Troponin I is the inhibitory subunit of troponin, the thin
CC filament regulatory complex which confers calcium-sensitivity to
CC striated muscle actomyosin ATPase activity.
CC {ECO:0000256|ARBA:ARBA00001988}.
CC -!- SIMILARITY: Belongs to the troponin I family.
CC {ECO:0000256|ARBA:ARBA00009930}.
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DR EMBL; ADFV01023248; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3GWS8; -.
DR Ensembl; ENSNLET00000057831.1; ENSNLEP00000035697.1; ENSNLEG00000033080.1.
DR GeneTree; ENSGT01030000234588; -.
DR Proteomes; UP000001073; Chromosome 9.
DR GO; GO:0005861; C:troponin complex; IEA:InterPro.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.350; -; 1.
DR Gene3D; 6.10.250.180; -; 1.
DR InterPro; IPR001978; Troponin.
DR InterPro; IPR038077; Troponin_sf.
DR PANTHER; PTHR13738; TROPONIN I; 1.
DR PANTHER; PTHR13738:SF9; TROPONIN I, SLOW SKELETAL MUSCLE; 1.
DR Pfam; PF00992; Troponin; 1.
DR SUPFAM; SSF90250; Troponin coil-coiled subunits; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073}.
FT COILED 8..60
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 168 AA; 19499 MW; 1B8684653122E168 CRC64;
ILMLAKAKEC WEQEHEEREA EKVRYLAERI PTLQTRGLSL SALQDLCREL HAKVEVVDEE
RYDIEAKCLH NTREIKDLKL KVMDLRGKFK RPPLRRVRVS ADAMLRALLG SKHKVSMDLR
ANLKSVKKED TEKERPVEVG DWRKNVEAMS GMEGRKKMFD AAKSPTSQ
//
