ID A0A2I3GXY9_NOMLE Unreviewed; 156 AA.
AC A0A2I3GXY9;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=MBD domain-containing protein {ECO:0000259|PROSITE:PS50982};
GN Name=MECP2 {ECO:0000313|Ensembl:ENSNLEP00000036087.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000036087.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000036087.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000036087.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ADFV01117798; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01117799; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01117800; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01117801; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01117802; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01117803; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01117804; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01117805; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01117806; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01117807; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3GXY9; -.
DR STRING; 61853.ENSNLEP00000036087; -.
DR Ensembl; ENSNLET00000047052.1; ENSNLEP00000036087.1; ENSNLEG00000013783.3.
DR GeneTree; ENSGT00530000063687; -.
DR InParanoid; A0A2I3GXY9; -.
DR OMA; CCCSEEK; -.
DR Proteomes; UP000001073; Chromosome X.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR CDD; cd01396; MeCP2_MBD; 1.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR InterPro; IPR045138; MeCP2/MBD4.
DR InterPro; IPR001739; Methyl_CpG_DNA-bd.
DR PANTHER; PTHR15074; METHYL-CPG-BINDING PROTEIN; 1.
DR PANTHER; PTHR15074:SF6; METHYL-CPG-BINDING PROTEIN 2; 1.
DR Pfam; PF01429; MBD; 1.
DR SMART; SM00391; MBD; 1.
DR SUPFAM; SSF54171; DNA-binding domain; 1.
DR PROSITE; PS50982; MBD; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073}.
FT DOMAIN 102..156
FT /note="MBD"
FT /evidence="ECO:0000259|PROSITE:PS50982"
FT REGION 1..128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..61
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 95..121
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 156 AA; 16915 MW; FBA336D1BD7A8778 CRC64;
MAAAAAAAPS GGGGGGEEER LEEKSEDQDL QGLKDKPLKF KKVKKDKKEE KEGKHEPVQP
SAHHSAEPAE AGKAETSEGS GSAPAVPEAS ASPKQRRSII RDRGPMYDDP TLPEGWTRKL
KQRKSGRSAG KYDVYLINPQ GKAFRSKVEL IAYFEK
//
