ID A0A2I3GZ75_NOMLE Unreviewed; 352 AA.
AC A0A2I3GZ75;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Nectin cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSNLEP00000036581.1};
GN Name=NECTIN1 {ECO:0000313|Ensembl:ENSNLEP00000036581.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000036581.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000036581.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000036581.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the nectin family.
CC {ECO:0000256|ARBA:ARBA00007810}.
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DR EMBL; ADFV01057139; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01057140; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01057141; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01057142; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01057143; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01057144; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01057145; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01057146; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01057147; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01057148; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3GZ75; -.
DR Ensembl; ENSNLET00000052239.1; ENSNLEP00000036581.1; ENSNLEG00000007399.2.
DR GeneTree; ENSGT00940000156933; -.
DR Proteomes; UP000001073; Chromosome 15.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0042802; F:identical protein binding; IEA:UniProt.
DR CDD; cd05890; IgC1_2_Nectin-1_like; 1.
DR CDD; cd05886; IgV_1_Nectin-1_like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR041850; Nectin-1_Ig2.
DR InterPro; IPR041849; Nectin-1_IgV1.
DR PANTHER; PTHR23277:SF69; NECTIN-1; 1.
DR PANTHER; PTHR23277; NECTIN-RELATED; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 2.
DR SMART; SM00406; IGv; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..352
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014140815"
FT DOMAIN 26..141
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 247..333
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 352 AA; 39147 MW; 1043388510390E57 CRC64;
MARMGLAGAA GRWWGFALGL TAFFLPGAHS QVVQVNDSMY GFIGTDVVLH CSFANPLPSV
KITQVTWQKS TNGSKQNVAI YNPSMGVSVL APYRERVEFL RPSFTDGTIR LSRLELEDEG
VYICEFATFP TGNRESQLNL TVMAKPTNWI EGTQAVLQAK KGQDDKVLVA TCTSANGKPP
SVVSWETRLK GEAEYQEIRN PNGTVTVISR YRLVPSREAH QQSLACIVNY HMDRFKESLT
LNVQYEPEVT IEGFDGWYLQ RMDVKLTCKA DANPPATEYH WTTLNGSLPK GVEAQNRTLF
FKGPINYSLA GTYICEATNP IGTRSGQVEV NITAFFCQLI YPGKGRTRGR MF
//
