ID   A0A2I3H0U3_NOMLE        Unreviewed;       701 AA.
AC   A0A2I3H0U3;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=G protein signaling modulator 1 {ECO:0000313|Ensembl:ENSNLEP00000037130.1};
GN   Name=GPSM1 {ECO:0000313|Ensembl:ENSNLEP00000037130.1};
OS   Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC   Nomascus.
OX   NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000037130.1, ECO:0000313|Proteomes:UP000001073};
RN   [1] {ECO:0000313|Ensembl:ENSNLEP00000037130.1, ECO:0000313|Proteomes:UP000001073}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Gibbon Genome Sequencing Consortium;
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSNLEP00000037130.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the GPSM family.
CC       {ECO:0000256|ARBA:ARBA00006600}.
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DR   EMBL; ADFV01120703; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01120704; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01120705; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01120706; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01120707; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01120708; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01120709; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A2I3H0U3; -.
DR   STRING; 61853.ENSNLEP00000037130; -.
DR   Ensembl; ENSNLET00000039971.1; ENSNLEP00000037130.1; ENSNLEG00000008142.2.
DR   GeneTree; ENSGT00940000154667; -.
DR   InParanoid; A0A2I3H0U3; -.
DR   OMA; HANIANC; -.
DR   Proteomes; UP000001073; Chromosome 8.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0030695; F:GTPase regulator activity; IEA:InterPro.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR   InterPro; IPR003109; GoLoco_motif.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR45954:SF2; G-PROTEIN-SIGNALING MODULATOR 1; 1.
DR   PANTHER; PTHR45954; LD33695P; 1.
DR   Pfam; PF02188; GoLoco; 4.
DR   Pfam; PF13374; TPR_10; 1.
DR   Pfam; PF13424; TPR_12; 2.
DR   SMART; SM00390; GoLoco; 4.
DR   SMART; SM00028; TPR; 6.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   PROSITE; PS50877; GOLOCO; 4.
DR   PROSITE; PS50005; TPR; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW   TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW   ProRule:PRU00339}.
FT   REPEAT          275..308
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REGION          416..518
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          635..656
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          670..701
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        446..466
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        481..500
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   701 AA;  77617 MW;  AAFC64639FB60109 CRC64;
     MPSPAVEGPP LALSLAEKAV CKVVYGAPRP RPLLLPVGLE LWLYVQKMRN LQRKRMEASC
     LELALEGERL CKAGDFKAGV AFFEAAVQVG TEDLKTLSAI YSQLGNAYFY LKEHGRALEY
     HKHDLLLART IGDRMGEAKA SGNLGNTLKV LGRFDEAAVC CQRHLSIAQE QGDKLYNIGN
     VYHAKGKQLS WNAANAAQDP GHLPPDVRET LCKASEFYER NLSLVKELGD RAAQGRAYGN
     LGNTHYLLGN FTEATTFHKE RLAIAKEFGD KAAERRAYSN LGNAHVFLGR FDVAAEYYKK
     TLQLSRQLRD QAVEAQACYS LGNTYTLLQD YERAAEYHLR HLLIAQELAD RVGEGRACWS
     LGNAYVSMGR PAQALTFAKK HLQISQEIGD RHGELTARMN VAQLQLALGR LTSPAASEKP
     DLAGYEAQGA RPKRTQRLST ETWDLLRLPL EREQNGDSHH SGDWRGPSRD SLPLPVRSRK
     YQEGPDAERR PREGSHSPLD SADVRVHVPR TSIPRAPSSD EECFFDLLTK FQSSRMDDQR
     CPLDDGQAGA AEATAAPTLE DRIAQTSMTA SPQTEEFFDL IASSQSRRLD DQRASVGSLP
     GLRITHSNAG HLRGHGDPQE PGDDFFNMLI KYQSSRIDDQ RCPPPDVLPR GPTMPDEDFF
     SLIQRVQAKR MDEQRVDLAG GPEQGAGGPP EPQQQCQPGA S
//