ID A0A2I3H278_NOMLE Unreviewed; 110 AA.
AC A0A2I3H278;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Transmembrane protein 50B {ECO:0000256|ARBA:ARBA00041170};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000037557.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000037557.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000037557.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: May form homotrimers or homodimers.
CC {ECO:0000256|ARBA:ARBA00038714}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004653}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004653}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the UPF0220 family.
CC {ECO:0000256|ARBA:ARBA00005335}.
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DR EMBL; ADFV01052344; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3H278; -.
DR STRING; 61853.ENSNLEP00000037557; -.
DR Ensembl; ENSNLET00000056606.1; ENSNLEP00000037557.1; ENSNLEG00000033944.1.
DR GeneTree; ENSGT00940000155131; -.
DR InParanoid; A0A2I3H278; -.
DR OMA; PEYECID; -.
DR Proteomes; UP000001073; Chromosome 10.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR007919; UPF0220.
DR PANTHER; PTHR13180; SMALL MEMBRANE PROTEIN-RELATED; 1.
DR PANTHER; PTHR13180:SF2; TRANSMEMBRANE PROTEIN 50B; 1.
DR Pfam; PF05255; UPF0220; 1.
PE 3: Inferred from homology;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 24..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 48..68
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 80..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 110 AA; 12533 MW; F2866E3966A5A5A0 CRC64;
MAVFLDNFHW PECECIDWSE RRNVVASVVT GILFFTAVVY CRPEQLNHAF HTCGVFPTLA
FFMLNAVSNA QVRGDSYESG FWLFVGFMLM FGVLTASMWI LFGAYVTQPL
//
