ID A0A2I3H714_NOMLE Unreviewed; 617 AA.
AC A0A2I3H714;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Plastin-3 {ECO:0000256|ARBA:ARBA00039437};
DE AltName: Full=T-plastin {ECO:0000256|ARBA:ARBA00041485};
GN Name=PLS3 {ECO:0000313|Ensembl:ENSNLEP00000039301.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000039301.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000039301.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000039301.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; ADFV01008466; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01008467; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01008468; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01008469; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01008470; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01008471; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012354413.1; XM_012498959.1.
DR AlphaFoldDB; A0A2I3H714; -.
DR Ensembl; ENSNLET00000050021.1; ENSNLEP00000039301.1; ENSNLEG00000014671.3.
DR GeneTree; ENSGT00950000183097; -.
DR Proteomes; UP000001073; Chromosome X.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0051017; P:actin filament bundle assembly; IEA:InterPro.
DR CDD; cd21328; CH_PLS3_rpt2; 1.
DR CDD; cd21331; CH_PLS3_rpt3; 1.
DR CDD; cd21334; CH_PLS3_rpt4; 1.
DR CDD; cd21292; CH_PLS_rpt1; 1.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 4.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR039959; Fimbrin/Plastin.
DR PANTHER; PTHR19961; FIMBRIN/PLASTIN; 1.
DR PANTHER; PTHR19961:SF32; PLASTIN-3; 1.
DR Pfam; PF00307; CH; 4.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00033; CH; 4.
DR SMART; SM00054; EFh; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 2.
DR PROSITE; PS50021; CH; 4.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 30..65
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 101..217
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 245..365
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 384..493
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 505..614
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
SQ SEQUENCE 617 AA; 69398 MW; 1931ABC6883BE2D3 CRC64;
MEYLNSNGFI CDYELHELFK EANMPLPGYK VREIIQKLML DGDRNKDGKI SFDEFVYIFQ
EVKSSDIAKT FRKAINRKEG ICALGGTSEL SSEGTQHSYS EEEKYAFVNW INKALENDPD
CRHVIPMNPN TDDLFKAVGD GIVLCKMINL SVPDTIDERA INKKKLTPFI IQENLNLALN
SASAIGCHVV NIGAEDLRAG KPHLVLGLLW QIIKIGLFAD IELSRNEALA ALLRDGETLE
ELMKLSPEEL LLRWANFHLE NSGWQKINNF SADIKLIDFS NSVKDSKAYF HLLNQIAPKG
QKEGEPRIDI NMSGFNETDD LKRAESMLQQ ADKLGCRQFV TPADVVSGNP KLNLAFVANL
FNKYPALTKP ENQDIDWTLL EGETREERTF RNWMNSLGVN PHVNHLYADL QDALVILQLY
ERIKVPVDWS KVNKPPYPKL GANMKKLENC NYAVELGKHP AKFSLVGIGG QDLNDGNQTL
TLALVWQLMR RYTLNVLEDL GDGQKANDDI IVNWVNRTLS EAGKSTSIQS FKDKTISSSL
AVVDLIDAIQ PGCINYDLVK SGNLTEDDKH NNAKYAVSMA RRIGARVYAL PEDLVEVKPK
MVMTVFACLM GRGMKRV
//
