ID A0A2I3HA98_NOMLE Unreviewed; 278 AA.
AC A0A2I3HA98;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=F-box protein 8 {ECO:0000313|Ensembl:ENSNLEP00000040574.1};
GN Name=FBXO8 {ECO:0000313|Ensembl:ENSNLEP00000040574.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000040574.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000040574.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000040574.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01179285; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01179286; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01179287; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01179288; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01179289; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012363680.1; XM_012508226.1.
DR AlphaFoldDB; A0A2I3HA98; -.
DR SMR; A0A2I3HA98; -.
DR Ensembl; ENSNLET00000034731.1; ENSNLEP00000040574.1; ENSNLEG00000006678.3.
DR GeneTree; ENSGT00940000158356; -.
DR Proteomes; UP000001073; Chromosome 7b.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF01369; Sec7; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001073}.
FT DOMAIN 92..273
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
SQ SEQUENCE 278 AA; 32426 MW; D0615626C2EBF06F CRC64;
MGQGLWRVVR NQQLQQEGYS EQGYLTREQS RRMAASNISN TNHRKQVQGG IDIYHLLKDL
ANDELLWQGL CKSTWGHCSI YNKNPPLGFS FRKLYMQLDE GSLTFNANPD EGVNYFMSKG
ILDDSPKEIA KFIFCTRTLN WKKLRIYLDE RRDVLDDLVT LHNFRNQFLP NALREFFRHI
HAPEERGEYL ETLITKFSHR FCACNPDLMR ELGLSPDAVY VLCYSLILLS IDLTSPHVKN
KMSKREFIRN TRRAAQNISE DFVGHLYDNI YLIGHVAA
//
