ID A0A2I3HDI0_NOMLE Unreviewed; 1559 AA.
AC A0A2I3HDI0;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Arginine-glutamic acid dipeptide repeats {ECO:0000313|Ensembl:ENSNLEP00000041713.1};
GN Name=RERE {ECO:0000313|Ensembl:ENSNLEP00000041713.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000041713.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000041713.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000041713.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01080338; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01080339; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01080340; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01080341; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01080342; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01080343; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01080344; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01080345; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01080346; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01080347; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Ensembl; ENSNLET00000049016.1; ENSNLEP00000041713.1; ENSNLEG00000008822.3.
DR GeneTree; ENSGT00940000153615; -.
DR Proteomes; UP000001073; Chromosome 24.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd11661; SANT_MTA3_like; 1.
DR CDD; cd00202; ZnF_GATA; 1.
DR Gene3D; 2.30.30.490; -; 1.
DR Gene3D; 4.10.1240.50; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR002951; Atrophin-like.
DR InterPro; IPR001025; BAH_dom.
DR InterPro; IPR043151; BAH_sf.
DR InterPro; IPR000949; ELM2_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR017884; SANT_dom.
DR InterPro; IPR000679; Znf_GATA.
DR PANTHER; PTHR13859:SF12; ARGININE-GLUTAMIC ACID DIPEPTIDE REPEATS PROTEIN; 1.
DR PANTHER; PTHR13859; ATROPHIN-RELATED; 1.
DR Pfam; PF03154; Atrophin-1; 1.
DR Pfam; PF01426; BAH; 1.
DR Pfam; PF01448; ELM2; 1.
DR Pfam; PF00320; GATA; 1.
DR SMART; SM00439; BAH; 1.
DR SMART; SM01189; ELM2; 1.
DR SMART; SM00717; SANT; 1.
DR SMART; SM00401; ZnF_GATA; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51038; BAH; 1.
DR PROSITE; PS51156; ELM2; 1.
DR PROSITE; PS51293; SANT; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 103..287
FT /note="BAH"
FT /evidence="ECO:0000259|PROSITE:PS51038"
FT DOMAIN 271..374
FT /note="ELM2"
FT /evidence="ECO:0000259|PROSITE:PS51156"
FT DOMAIN 378..430
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT REGION 1..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 451..482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 529..1120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1149..1239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..38
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..75
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 451..473
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 543..558
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 583..613
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 614..657
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 658..674
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 675..694
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 695..735
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 736..750
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 751..783
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 794..816
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 817..831
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 861..899
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 900..936
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 967..1043
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1044..1059
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1149..1191
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1559 AA; 171663 MW; C7F77790E327533A CRC64;
MTADKDKDKD KEKDRDRDRD REREKRDKAR ESENSRPRRS CTLEGGAKNY AESDHSEDED
NDNNSATAEE STKKNKKKPP KKKSRYERTD TGEITSYITE DDVVYRPGDC VYIESRRPNT
PYFICSIQDF KLVHNSQACC RSPTPALCDP PACSLPVASQ PPQHLSEAGR GPVGSKRDHL
LMNVKWYYRQ SEVPDSVYQH LVQDRHNEND SGRELVITDP VIKNRELFIS DYVDTYHAAA
LRGKCNISHF SDIFAAREFK ARLFIINTCL DCDLLIPVLQ AKLPDLQPFP SPDGDTVTQH
EELVWMPGVN DCDLLMYLRA ARSMAAFAGM CDGGSTEDGC VAASRDDTTL NALNTLHESG
YDAGKALQRL VKKPVPKLIE KCWTEDEVKR FVKGLRQYGK NFFRIRKELL PNKETGELIT
FYYYWKKTPE AASSRAHRRH RRQAVFRRIK TRTASTPVNT PSRPPSSEFL DLSSASEDDF
DSEDSEQELK GYACRHCFTT TSKDWHHGGR ENILLCTDCR IHFKKYGELP PIEKPVDPPP
FMFKPVKEED DGLSGKHSMR TRRSRGSMST LRSGRKKQPA SPDGRTSPIN EDIRSSGRNS
PSAASTSSND SKAETLKKSA KKVKEEASSP LKSNKRQREK VASDTEEADR TSSKKTKTQE
ISRPNSPSEG EGESSDSRSV NDEGSSDPKD IDQDNRSTSP SIPSPQDNES DSDSSAQQQM
LQAQPPALQA PTGVTPAPSS APPGTPQLPT PGSMPSATAV PPQGSPTASQ APNQPQAPSA
PVPHTHIQQA PALHPQRPPS PHPPPHPSPH PPLQPLTGSA GQPSAPSHAQ LPLHSQGPPG
PHSLQAGPLL QHPGPPQPFG LPTQASQGQA PLGTSPSAAH PHASLQLPAS QSALQSQQPP
REQPLPPAPL AMPHIKPPPT TPIPQLPAPQ AHKHPPHLSG PSPFSMNANL PPPPALKPLS
SLSTHHPPSA HPPPLQLMPQ SQPLPSSPAQ PPGLTQSQNL PPPPASHPPT GLHQVAPQPP
FAQHPFVPGG PPPITPPTCS STSTPPAGPS TSAQPPCSGA VASGGSIAGG SSCPLPTVQI
KEEALDDAEE PESPPPPPRS PSPEPTVVDT PSHASQSARF YKHLDRGYNS CARTDLYFMP
LAGSKLAKKR EEAIEKAKRE AEQKAREERE REKEKEKERE REREREHSGD PSRFLFLLQK
ASSSAHEGRL SDPQLSGPGH LRPSFEPPPT TIAAVPPYIG PDTPALRTLS EYARPHVMSP
TNRNHPFYMP LNPTDPLLAY HMPGLYNVDP TIRERELRER EIREREIRER ELRERMKPGF
EVKPPELDPL HPAANPMEHF ARHSALTIPP TAGPHPFASF HPGLNPLERE RLALAGPQLR
PEMSYPDRLA AERIHAERMA SLTSDPLARL QMFNVTPHHH QHSHIHSHLH LHQQDPLHQG
SAGPVHPLVD PLTAGPHLAR FPYPPGTLPN PLLGQPPHEH EMLRHPVFGT PYPRDLPGAI
PPPMSAAHQL QAMHAQSAEL QRLAMEQQWL HGHPHMHGGH LPSQEDYYSR LKKEGDKQL
//
