ID A0A2I3HFQ4_NOMLE Unreviewed; 971 AA.
AC A0A2I3HFQ4;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Smoothelin {ECO:0000313|Ensembl:ENSNLEP00000042345.1};
GN Name=SMTN {ECO:0000313|Ensembl:ENSNLEP00000042345.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000042345.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000042345.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000042345.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01177707; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01177708; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01177709; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003258142.1; XM_003258094.3.
DR AlphaFoldDB; A0A2I3HFQ4; -.
DR Ensembl; ENSNLET00000054945.1; ENSNLEP00000042345.1; ENSNLEG00000004083.3.
DR GeneTree; ENSGT00940000161655; -.
DR Proteomes; UP000001073; Chromosome 7b.
DR CDD; cd21259; CH_SMTNB; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR022189; SMTN.
DR PANTHER; PTHR23167; CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED; 1.
DR PANTHER; PTHR23167:SF52; SMOOTHELIN; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF12510; Smoothelin; 3.
DR SMART; SM00033; CH; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR PROSITE; PS50021; CH; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073}.
FT DOMAIN 855..961
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REGION 188..511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 673..823
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 86..115
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 197..224
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..264
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 289..304
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..319
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 356..378
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..446
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 673..693
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 699..774
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 794..808
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 971 AA; 105106 MW; EF6A4AB63B5124C8 CRC64;
MGGMGAPGDL HAACPSSTSR DALRLGPEFE FDLRHSAGCP GDLGFFPLDR DTEAGGSGCL
PTWLPLRRLA RGWLEVTADL AERRRIRSAI RELQRQELER EEEALASKRF RAERQDNKEN
WLHSQQREAE QQAALARLAG QLESMNDVEE LTALLRSAGE YEERKLIRAA IRRVRAQEIE
AATLAGRLCS GRPNSGSRED SKGRAAHRLE QCEVPEREEQ EQQAEVSKPT PTPEGTSQDV
TTVTLLLRAP PGSTSSSPAS PSSSPTPASL EPPLEPAEAQ CLTAEVPGSP EPLPSPPKTT
SPEPQESPTL PSTEGQVVNK LLSGPKETPA AQSPTRGPSD TKRADVAGPR PCQRSLSVLS
PRQPAQNRES TRLAIGPSSF QRAGSVRDRV HKFTSDSPMA ARLQDGTSRA ALSPLTPARL
LGPSLTSTTP ASSSSGSSSR GPSDTSSRFS KEQRRVAQPL AQLRSCPQEE GPRGRGLAAR
PLENRAGGPV ARSEEPGAPL PVAVGTTEPG GSMKTTFTIE IKDGRGQAST GRVLLPTGNQ
RAELTLGLRA PPTLLSTSSG GKSTITRVNS PGTLARLGSV THVTSFSHAP PSSRGGCSIK
MEPEPAEPLA AAVEAANGAE QTRVSKAPEG QNPLSAEELM TIEDEGVLDK MLDQSTDFEE
RKLIRAALRE LRQRKRDQRD KERERRLQEA RGRPGEGRGN TATETTMRHS QRAADGSAVS
TVTKTERLVH SNDGTRTART TTVESSFVRR SENGSGSTMM QTKTFSSSSS SKKMGSIFDR
EDQASPRAGS LAALEKRQAE KKKELMKAQS LPKTSASQAR KAMIEKLEKE GAAGSPGGPR
AAVQRATSFG VPNANSIKQM LLDWCRAKTR GYEHVDIQNF SSSWSDGMAF CALVHNFFPE
AFDYGQLSPQ NRRQNFEVAF SSAETHADCP QLLDTEDMVR LREPDWKCVY TYIQEFYRCL
VQKGLVKTKK S
//
