ID A0A2I3HGH4_NOMLE Unreviewed; 362 AA.
AC A0A2I3HGH4;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Paired box 5 {ECO:0000313|Ensembl:ENSNLEP00000042620.1};
GN Name=PAX5 {ECO:0000313|Ensembl:ENSNLEP00000042620.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000042620.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000042620.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000042620.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; ADFV01016547; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01016548; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01016549; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01016550; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01016551; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01016552; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01016553; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01016554; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01016555; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01016556; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012364664.1; XM_012509210.1.
DR AlphaFoldDB; A0A2I3HGH4; -.
DR Ensembl; ENSNLET00000048536.1; ENSNLEP00000042620.1; ENSNLEG00000003664.2.
DR GeneID; 100586040; -.
DR CTD; 5079; -.
DR GeneTree; ENSGT00940000159636; -.
DR OrthoDB; 5393942at2759; -.
DR Proteomes; UP000001073; Chromosome 8.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00131; PAX; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR043182; PAIRED_DNA-bd_dom.
DR InterPro; IPR001523; Paired_dom.
DR InterPro; IPR022130; Pax2_C.
DR InterPro; IPR043565; PAX_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR45636:SF20; PAIRED BOX PROTEIN PAX-5; 1.
DR PANTHER; PTHR45636; PAIRED BOX PROTEIN PAX-6-RELATED-RELATED; 1.
DR Pfam; PF00292; PAX; 1.
DR Pfam; PF12403; Pax2_C; 1.
DR PRINTS; PR00027; PAIREDBOX.
DR SMART; SM00351; PAX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00034; PAIRED_1; 1.
DR PROSITE; PS51057; PAIRED_2; 1.
PE 4: Predicted;
KW Paired box {ECO:0000256|ARBA:ARBA00022724};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 16..142
FT /note="Paired"
FT /evidence="ECO:0000259|PROSITE:PS51057"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 182..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 362 AA; 38920 MW; 64C0B3D758CC4DEC CRC64;
MDLEKNYPTP RTSRTGHGGV NQLGGVFVNG RPLPDVVRQR IVELAHQGVR PCDISRQLRV
SHGCVSKILG RYYETGSIKP GVIGGSKPKV ATPKVVEKIA EYKRQNPTMF AWEIRDRLLA
ERVCDNDTVP SVSSINRIIR TKVQQPPNQP VPASSHSIVS TGSVTQVSSV STDSAGSSYS
ISGILGITSP SADTNKRKRD EGIQESPVPN GHSLPGRDFL RKQMRGDLFT QQQLEVLDRV
FERQHYSDIF TTTEPIKPEQ TTEYSAMASL AGGLDDMKAN LASPTPADIG SSVPGPQSYP
IVTGRDLAST TLPGYPPHVP PAGQGSYSAP TLTGMVPGSP YYYSAATRGA APPAAATAYD
RH
//
