ID A0A2I3HGW3_NOMLE Unreviewed; 1159 AA.
AC A0A2I3HGW3;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=EH domain binding protein 1 {ECO:0000313|Ensembl:ENSNLEP00000042849.1};
GN Name=EHBP1 {ECO:0000313|Ensembl:ENSNLEP00000042849.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000042849.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000042849.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000042849.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01010111; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01010112; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01010113; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01010114; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01010115; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01010116; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01010117; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01010118; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01010119; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01010120; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003262488.1; XM_003262440.3.
DR AlphaFoldDB; A0A2I3HGW3; -.
DR Ensembl; ENSNLET00000046182.1; ENSNLEP00000042849.1; ENSNLEG00000009764.3.
DR GeneID; 100580490; -.
DR KEGG; nle:100580490; -.
DR CTD; 23301; -.
DR GeneTree; ENSGT00940000157597; -.
DR OrthoDB; 2881296at2759; -.
DR Proteomes; UP000001073; Chromosome 14.
DR CDD; cd21254; CH_EHBP1; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR InterPro; IPR022735; bMERB_dom.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR019448; NT-C2.
DR PANTHER; PTHR23167; CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED; 1.
DR PANTHER; PTHR23167:SF43; EH DOMAIN-BINDING PROTEIN 1; 1.
DR Pfam; PF12130; bMERB_dom; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF10358; NT-C2; 1.
DR SMART; SM00033; CH; 1.
DR SMART; SM01203; DUF3585; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR PROSITE; PS51848; BMERB; 1.
DR PROSITE; PS51840; C2_NT; 1.
DR PROSITE; PS50021; CH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001073}.
FT DOMAIN 8..158
FT /note="C2 NT-type"
FT /evidence="ECO:0000259|PROSITE:PS51840"
FT DOMAIN 407..512
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 984..1140
FT /note="BMERB"
FT /evidence="ECO:0000259|PROSITE:PS51848"
FT REGION 244..268
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 325..404
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 580..639
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 741..769
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 801..829
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 886..923
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 954..993
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1126..1159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 374..393
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 597..639
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 803..817
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 887..907
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 908..923
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 955..993
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1159 AA; 132095 MW; 278BF6DCDD7FDCEA CRC64;
MASVWKRLQR VGKHASKFQF VASYQELMVE CTKKWQPDKL VVVWTRRSRR KSSKAHSWQP
GIKNPYRGVV VWPVPENIEI TVTLFKDPHA EEFEDKEWTF VIENESPSGR RKALATSSIN
MKQYASPMPT QTDVKLKFKP LSKKVVSATL QFSLSCIFLR EGKATDEDMQ SLASLMSMKQ
ADIGNLDDFE EDNEDDDENR VNQEEKAAKI TELINKLNFL DEAEKDLATM NSNPFDDSDV
AELNPFGDPD SEEPITETAS PRKTEDSFYN NSYNPFKEVQ TPQYLNPFDE PEAFVTIKDS
PPQSTKRKNI RPVDMSKYLY ADSAKTEEEL DESNPFYEPK STPPPNNLVN PVQELETESR
VKRKAPAPPV LSTKTGVVNE NTVSAGKDLS TSPKPSPIPS PVLGRKPNAS QSLLVWCKEV
TKNYRGVKIT NFTTSWRNGL SFCAILHHFR PDLIDYKSLN PQDIKENNKK AYDGFASIGI
SRLLEPSDMV LLAIPDKLTV MTYLYQIRAH FSGQELNVVQ IEENSSKSTY KVGNYETDTN
SSVDQEKFYA ELSDLKREPE PQQPISGAVD FLSQDDSVFV NDSGVGESES EHQTPDDHLS
PSTASPCCRR TKSDTEPQKS QQSSGRTSGS DDPGICSNTD STQAQVLLGK KRLLKAEALE
LSDLYVSDKK KDVSPPFICE ETDEQKLRTL DIGSNLEKEK LENSRSLECR SDPESPIKKT
SLSPISKLGY SYSRDLDLAK KKHASLRQTE SDPDADRTTL NHADHSSKIV QHRMLSRQEE
LKERARVLLE QARRDAALKA GNKHNTNAAT PFCNRQLSDQ QDEERRRQLR ERARQLIAEA
RSGVKMSELP SYGEMAAEKL KERSKASGEQ NSKLVDLKLK KLLEVQPQVA NSPSSAAQKA
VTESSEQDMK NGTEDLRTER LQKTTERFRN PVVFSKDSTV RKTQLQSFSQ YIENRPEMKR
QRSIQEDTKK GNEEKAAITE TQRKPSEDEV LNKGFKDTSQ YVVGELAALE NEQKQIDTRA
ALVEKRLRYL MDTGRNTEEE EAMMQEWFML VNKKNALIRR MNQLSLLEKE HDLERRYELL
NRELRAMLAI EDWQKTEAQK RREQLLLDEL VALVNKRDAL VRDLDAQEKQ AEEEDEHLER
TLEQNKGKMA KKEEKCVLQ
//
