ID A0A2I3HH00_NOMLE Unreviewed; 504 AA.
AC A0A2I3HH00;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Double-stranded RNA-binding protein Staufen homolog 2 {ECO:0000256|ARBA:ARBA00024122};
GN Name=STAU2 {ECO:0000313|Ensembl:ENSNLEP00000042928.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000042928.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000042928.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000042928.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01050322; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01050323; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01050324; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01050325; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01050326; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01050327; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01050328; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01050329; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01050330; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01050331; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3HH00; -.
DR Ensembl; ENSNLET00000057482.1; ENSNLEP00000042928.1; ENSNLEG00000001342.3.
DR GeneTree; ENSGT00940000154977; -.
DR Proteomes; UP000001073; Chromosome 16.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd19882; DSRM_STAU2_rpt2; 1.
DR CDD; cd19884; DSRM_STAU2_rpt3; 1.
DR CDD; cd19886; DSRM_STAU2_rpt4; 1.
DR Gene3D; 3.30.160.20; -; 4.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR044464; STAU2_DSRM_2.
DR InterPro; IPR044473; STAU2_DSRM_3.
DR InterPro; IPR044474; STAU2_DSRM_4.
DR InterPro; IPR032478; Staufen_C.
DR PANTHER; PTHR46054:SF1; DOUBLE-STRANDED RNA-BINDING PROTEIN STAUFEN HOMOLOG 2; 1.
DR PANTHER; PTHR46054; MATERNAL EFFECT PROTEIN STAUFEN; 1.
DR Pfam; PF00035; dsrm; 3.
DR Pfam; PF16482; Staufen_C; 1.
DR SMART; SM00358; DSRM; 3.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 3.
DR PROSITE; PS50137; DS_RBD; 3.
PE 4: Predicted;
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00266}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 42..77
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 103..170
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 203..271
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 74..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 283..305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 470..504
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 488..504
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 504 AA; 55347 MW; 89B3B13992F13969 CRC64;
MKRGEPAIYR PLDPKPFPNY RANYNFRGMY NQRYHCPVPK IFYVQLTVGN NEFFGEGKTR
QAARHNAAMK ALQALQNEPI PERSPQNGES GKDMDDDKDA NKSEISLVFE IALKRNMPVS
FEVIKESGPP HMKSFVTRVS VGEFSAEGEG NSKKLSKKRA ATTVLQELKK LPPLPGVEKP
KLFFKKRPKT IVKAGPEYGQ GMNPISRLAQ IQQAKKEKEP DYVLLSERGM PRRREFVMQV
KVGNEVATGT GPNKKIAKKN AAEAMLLQLG YKASTNLQDQ LEKTGENKGW SGPKPGFPEP
TNNTPKGILH LSPDVYQEME ASRHKVISGT TLGYLSPKDM NQPSSSFFSI SATSNSSATI
ARELLMNGTS STAEAIGLKG SSPTPPCSPV PPSKQLEYLA RIQGFQVHYC DRQSGKECVT
CLTLAPVQMT FHAIGSSIEA SHDQAALSAL KQFSEQGLDP IDGAMNIEKG SLEKQAKHLR
EKADNNQAPP GSIAQDCKKS NSAV
//
