ID   A0A2I3HIJ5_NOMLE        Unreviewed;       560 AA.
AC   A0A2I3HIJ5;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Matrin 3 {ECO:0000313|Ensembl:ENSNLEP00000043429.1};
GN   Name=MATR3 {ECO:0000313|Ensembl:ENSNLEP00000043429.1};
OS   Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC   Nomascus.
OX   NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000043429.1, ECO:0000313|Proteomes:UP000001073};
RN   [1] {ECO:0000313|Ensembl:ENSNLEP00000043429.1, ECO:0000313|Proteomes:UP000001073}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Gibbon Genome Sequencing Consortium;
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSNLEP00000043429.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; ADFV01033118; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01033119; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A2I3HIJ5; -.
DR   Ensembl; ENSNLET00000044194.1; ENSNLEP00000043429.1; ENSNLEG00000009093.3.
DR   GeneTree; ENSGT00940000153322; -.
DR   Proteomes; UP000001073; Chromosome 2.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd12714; RRM1_MATR3; 1.
DR   CDD; cd12715; RRM2_MATR3; 1.
DR   Gene3D; 3.30.70.330; -; 2.
DR   InterPro; IPR034928; MATR3_RRM1.
DR   InterPro; IPR034930; MATR3_RRM2.
DR   InterPro; IPR000690; Matrin/U1-C_Znf_C2H2.
DR   InterPro; IPR003604; Matrin/U1-like-C_Znf_C2H2.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   PANTHER; PTHR15592; MATRIN 3/NUCLEAR PROTEIN 220-RELATED; 1.
DR   PANTHER; PTHR15592:SF2; MATRIN-3; 1.
DR   Pfam; PF13893; RRM_5; 1.
DR   SMART; SM00360; RRM; 2.
DR   SMART; SM00451; ZnF_U1; 1.
DR   SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR   PROSITE; PS50102; RRM; 2.
DR   PROSITE; PS50171; ZF_MATRIN; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW   RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          111..186
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   DOMAIN          209..284
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   DOMAIN          514..545
FT                   /note="Matrin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50171"
FT   REGION          49..106
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          301..497
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        301..360
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        361..377
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        403..448
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        462..490
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   560 AA;  62640 MW;  ADE45DC5BC8F910B CRC64;
     QTGVQWRDLG LLQPLPSRFN QHINGASHSR RCQLLLEIYP EWNPDNDTGH TMGDPFMLQQ
     STNPAPGILG PPPPSFHLGG PAVGPRGNLG AGNGNLQGPR HMQKGRVETS RVVHIMDFQR
     GKNLRYQLLQ LVEPFGVISN HLILNKINEA FIEMATTEDA QAAVDYYTTT PALVFGKPVR
     VHLSQKYKRI KKPEGKPDQK FDQKQELGRV IHLSNLPHSG YSDSAVLKLA EPYGKIKNYI
     LMRMKSQAFI EMETREDAMA MVDHCLKKAL WFQGRCVKVD LSEKYKKLVL RIPNRGIDLL
     KKDKSRKRSY SPDGKESPSD KKSKTDGSQK TESSTEGKEQ EEKSGEDGEK DTKDDQTEQE
     PNMLLESEDE LLVDEEEAAA LLESGSSVGD ETDLANLGDV ASDGKKEPSD KAVKKDASAS
     AAAKKKLKKV DKIEELDQEN EAALENGIKN EENTEPGAES AENADDPNKD TSENADGQSD
     ENKEDYTIPD EYRIGPYQPN VPVGIDYVIP KTGFYCKLCS LFYTNEEVAK NTHCSSLPHY
     QKLKKFLNKL AEERRQKKET
//