ID A0A2I3HML4_NOMLE Unreviewed; 335 AA.
AC A0A2I3HML4;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Ribonucleotide reductase regulatory TP53 inducible subunit M2B {ECO:0000313|Ensembl:ENSNLEP00000044752.1};
GN Name=RRM2B {ECO:0000313|Ensembl:ENSNLEP00000044752.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000044752.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000044752.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000044752.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the ribonucleoside diphosphate reductase small
CC chain family. {ECO:0000256|ARBA:ARBA00009303}.
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DR EMBL; ADFV01167686; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01167687; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01167688; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01167689; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3HML4; -.
DR Ensembl; ENSNLET00000039287.1; ENSNLEP00000044752.1; ENSNLEG00000003370.2.
DR GeneTree; ENSGT00390000013305; -.
DR OMA; LEPMFLG; -.
DR Proteomes; UP000001073; Chromosome 16.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0009263; P:deoxyribonucleotide biosynthetic process; IEA:InterPro.
DR CDD; cd01049; RNRR2; 1.
DR Gene3D; 1.10.620.20; Ribonucleotide Reductase, subunit A; 1.
DR InterPro; IPR009078; Ferritin-like_SF.
DR InterPro; IPR012348; RNR-like.
DR InterPro; IPR033909; RNR_small.
DR InterPro; IPR030475; RNR_small_AS.
DR InterPro; IPR000358; RNR_small_fam.
DR PANTHER; PTHR23409; RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN; 1.
DR PANTHER; PTHR23409:SF19; RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2 B; 1.
DR Pfam; PF00268; Ribonuc_red_sm; 1.
DR SUPFAM; SSF47240; Ferritin-like; 1.
DR PROSITE; PS00368; RIBORED_SMALL; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 171..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 335 AA; 39052 MW; 518C398281D56EF4 CRC64;
RSSSDTNENE IKSNEEPLLR KSSRRFVIFP IQYPDIWKMY KQAQASFWTA EEVDLSKDLP
HWNKLKADEK YFISHILAFF AASDGIVNEN LVERFSQEVQ VPEARCFYGF QILIENVHSE
MYSLLIDTYI RDPKKREFLF NAIETMPYVK KKADWALRWI ADRKSTFGER VVAFAAVEGV
FFSGSFAAIF WLKKRGLMPG LTFSNELISR DEGLHCDFAC LMFQYLVNKP SEERVREIIV
DAVKIEQEFL TEALPVGLIG MNCILMKQYI EFVADRLLVE LGFSKVFQAE NPFDFMENIS
LEGKTNFFEK RVSEYQRFAV MAETTDNVFT LDADF
//
