ID A0A2I3HMN0_NOMLE Unreviewed; 566 AA.
AC A0A2I3HMN0;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Solute carrier family 13 member 1 {ECO:0000313|Ensembl:ENSNLEP00000044879.1};
GN Name=SLC13A1 {ECO:0000313|Ensembl:ENSNLEP00000044879.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000044879.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000044879.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000044879.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family.
CC NADC subfamily. {ECO:0000256|ARBA:ARBA00006772}.
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DR EMBL; ADFV01195841; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01195842; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01195843; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3HMN0; -.
DR Ensembl; ENSNLET00000054887.1; ENSNLEP00000044879.1; ENSNLEG00000012101.2.
DR GeneTree; ENSGT01030000234550; -.
DR Proteomes; UP000001073; Chromosome 13.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015370; F:solute:sodium symporter activity; IEA:UniProt.
DR CDD; cd01115; SLC13_permease; 1.
DR InterPro; IPR031312; Na/sul_symport_CS.
DR InterPro; IPR001898; SLC13A/DASS.
DR PANTHER; PTHR10283; SOLUTE CARRIER FAMILY 13 MEMBER; 1.
DR PANTHER; PTHR10283:SF65; SOLUTE CARRIER FAMILY 13 MEMBER 1; 1.
DR Pfam; PF00939; Na_sulph_symp; 1.
DR PROSITE; PS01271; NA_SULFATE; 1.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|ARBA:ARBA00023201};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Sodium {ECO:0000256|ARBA:ARBA00023201};
KW Sodium transport {ECO:0000256|ARBA:ARBA00023201};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 52..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 314..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 353..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 441..472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 484..503
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 524..545
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 566 AA; 62593 MW; 098D4E51A02C91BB CRC64;
LYETEAECAY TLFVVATFWL TEALPLSVTA LLPSLMLPMF GIMPSKKVAS AYFKDFHLLL
IGVICLATSI EKWNLHKRIA LKMVMMVGVN PAWLTLGFMS STAFLSMWLS NTSTAAMVMP
IAEAVAQQII NAEAEVEATQ MTYFNGSTNH GLEVDESVNG HEINERKEKT NPVPGYNNDT
GKISSKVELE KNSGMGTKYR TKKGHMTCKL MCLCIAYSST IGGLTTITGT STNLIFAEYF
NTRYPDCHCL NFGSWFTFSF PAALIILLLS WIWLQWLFLG FNFKEMFKCG KTKTVQQKAC
AEVIKQEYQK LGPIRYQEIV TLVLFIIMAL LWFSRDPGFV PGWSALFSEY PGFATDSTVA
LLIGLLFFLI PAKRLTKTTP TGEIVAFDYS PLITWKEFQS FMPWDIAILV GGGFALADGC
EESGLSKWIG NKLSPLGSLP VWLIILISSL MVTSLTEVAS NPATITLFLP ILSPLTEAIH
VNPLYILIPS TLCTSFAFLL PVANPPNAIV FSYGHLKVID MVKAGLGVNI VGVAVVMLGI
CTWIVPMFDL YTYPSWAPAM SNETMP
//
