ID   A0A2I3HNH4_NOMLE        Unreviewed;       559 AA.
AC   A0A2I3HNH4;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=REM-1 domain-containing protein {ECO:0000259|PROSITE:PS51860};
GN   Name=LOC100582927 {ECO:0000313|Ensembl:ENSNLEP00000045188.1};
OS   Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC   Nomascus.
OX   NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000045188.1, ECO:0000313|Proteomes:UP000001073};
RN   [1] {ECO:0000313|Ensembl:ENSNLEP00000045188.1, ECO:0000313|Proteomes:UP000001073}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Gibbon Genome Sequencing Consortium;
RL   Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSNLEP00000045188.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; ADFV01007056; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ADFV01007057; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A2I3HNH4; -.
DR   Ensembl; ENSNLET00000052019.1; ENSNLEP00000045188.1; ENSNLEG00000034303.1.
DR   GeneTree; ENSGT00940000154339; -.
DR   Proteomes; UP000001073; Chromosome 4.
DR   GO; GO:0004697; F:diacylglycerol-dependent serine/threonine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd11622; HR1_PKN_1; 1.
DR   Gene3D; 1.10.287.160; HR1 repeat; 3.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR011072; HR1_rho-bd.
DR   InterPro; IPR036274; HR1_rpt_sf.
DR   InterPro; IPR037313; PKN_HR1_1.
DR   Pfam; PF02185; HR1; 2.
DR   SMART; SM00239; C2; 1.
DR   SMART; SM00742; Hr1; 3.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR   SUPFAM; SSF46585; HR1 repeat; 3.
DR   PROSITE; PS51860; REM_1; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01207};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001073}.
FT   DOMAIN          107..189
FT                   /note="REM-1"
FT                   /evidence="ECO:0000259|PROSITE:PS51860"
FT   REGION          99..120
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          330..360
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        105..120
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        332..360
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   559 AA;  63294 MW;  02817DEF61D738D1 CRC64;
     MASNPEWGEI LLTELQWDSR SLLFSENVSA VQKLDFSDTM VQQKLHDIKD RIKREIRKEL
     KIKEGAENLR KVTTDKKKFE ELRHKLQEVS AHIIVSDPED ITDCPRTPDT SNSDPRCSTS
     NNRLKALQKQ LDIELKVKQG LENMIQMYSN GSSKDRKLHG TAQQLLQDSK TKIEVIRMQI
     LLAVQTNELA FDNAKPVISP LELRVEELRH HFSIESAVAE GAKNVMKLLD SGKVTDRKAL
     SEAQKLDLLK YSLEQRLNEL PKNHPKSSII TEELSLVAAS PTLSPRQSMI STQNQYSTPS
     KPAALTGTLE VGLMGCQDIL ENVPGRSKAT SIALPGWSSS ETRSSFMSRT SKSKSGSSRN
     LLKTDDLSND VCAVLKLDNT VVGQSSWKAI SNQSWDQKFT LELDRSRELE ISVYWRDWRS
     LCAVRFLRLE DFLDNQRHGM CLYLEPQGTL FAEVTFLNPV IERRPKLQRQ KKIFSKQQGK
     TFLRAPQMNI NIATWGRLVR RAIHTVNHSG TFSPQAPVPT TVPVVDVRIP ELAPPAIFTE
     TLVLLISPLV SHVLYMYMI
//