ID A0A2I3HNN6_NOMLE Unreviewed; 365 AA.
AC A0A2I3HNN6;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=CD72 molecule {ECO:0000313|Ensembl:ENSNLEP00000045120.1};
GN Name=CD72 {ECO:0000313|Ensembl:ENSNLEP00000045120.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000045120.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000045120.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000045120.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01016709; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01016710; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003263414.1; XM_003263366.2.
DR AlphaFoldDB; A0A2I3HNN6; -.
DR STRING; 61853.ENSNLEP00000045120; -.
DR Ensembl; ENSNLET00000040877.1; ENSNLEP00000045120.1; ENSNLEG00000034608.1.
DR GeneTree; ENSGT00390000003668; -.
DR InParanoid; A0A2I3HNN6; -.
DR OMA; NWEDSQR; -.
DR OrthoDB; 3024335at2759; -.
DR Proteomes; UP000001073; Chromosome 8.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0005537; F:mannose binding; IEA:UniProtKB-KW.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR001304; C-type_lectin-like.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR039689; CD72.
DR InterPro; IPR016187; CTDL_fold.
DR PANTHER; PTHR15028:SF6; B-CELL DIFFERENTIATION ANTIGEN CD72; 1.
DR PANTHER; PTHR15028; CD72-RELATED; 1.
DR Pfam; PF00059; Lectin_C; 1.
DR SMART; SM00034; CLECT; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
DR PROSITE; PS50041; C_TYPE_LECTIN_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Immunity {ECO:0000256|ARBA:ARBA00022859};
KW Innate immunity {ECO:0000256|ARBA:ARBA00022588};
KW Lectin {ECO:0000256|ARBA:ARBA00023035};
KW Mannose-binding {ECO:0000256|ARBA:ARBA00023035};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 95..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 240..351
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT COILED 122..219
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 365 AA; 41229 MW; 0DC9F84E3D43B622 CRC64;
MAEAITYADL RFVKAPLKKS ISSRLGQDPG ADEDGELTYE NVQVPTVRGG PSSLASSVLG
DKAAVKSEQP TESWRAVTSP AVGRILPCRT ACLRYLLLGL LLTCLLLGVA AICLGVRYLQ
VSQQLQQMNR VLEATNSSLR QQLHLKITQL GQSAEDLQGS RRELAQSQEA LQVEQRAHQA
AEGQLQACQA DREKTKETLQ SEEQQRRALE QKLSNMENTL KPFFPCRSAD TCCPMGWIMH
QKSCFYISPT SKNWQESQKH CETLSSKLAT FSETYQQSHS YSTLNWLLPN RDSEDSYWNG
LSSNKDGKLT DDTQHTRTYA QSSRCTKVHK IWTWWKLESE ACRSYLPYIC EMTAFRFPHL
DSPLH
//
