ID A0A2I3HNV2_NOMLE Unreviewed; 475 AA.
AC A0A2I3HNV2;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Spectrin repeat containing nuclear envelope protein 1 {ECO:0000313|Ensembl:ENSNLEP00000045299.1};
GN Name=SYNE1 {ECO:0000313|Ensembl:ENSNLEP00000045299.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000045299.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000045299.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000045299.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus outer membrane
CC {ECO:0000256|ARBA:ARBA00004605}; Single-pass type IV membrane protein
CC {ECO:0000256|ARBA:ARBA00004605}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004605}.
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DR EMBL; ADFV01166707; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01166708; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01166709; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01166710; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01166711; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01166712; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01166713; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01166714; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01166715; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01166716; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3HNV2; -.
DR Ensembl; ENSNLET00000040615.1; ENSNLEP00000045299.1; ENSNLEG00000015419.2.
DR GeneTree; ENSGT00940000154481; -.
DR Proteomes; UP000001073; Chromosome 3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR CDD; cd21241; CH_SYNE1_rpt1; 1.
DR CDD; cd21243; CH_SYNE1_rpt2; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR039906; Anc-1/SYNE1/2-like.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR047290; CH_SYNE1_rpt1.
DR InterPro; IPR047291; CH_SYNE1_rpt2.
DR PANTHER; PTHR21524; SPECTRIN REPEAT CONTAINING NUCLEAR ENVELOPE PROTEIN 2; 1.
DR PANTHER; PTHR21524:SF7; SPECTRIN REPEAT CONTAINING, NUCLEAR ENVELOPE 1; 1.
DR Pfam; PF00307; CH; 2.
DR SMART; SM00033; CH; 2.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 10..124
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 168..273
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
SQ SEQUENCE 475 AA; 54572 MW; 338D7A0B520A63B8 CRC64;
MQRLQDEQEI VQKRTFTKWI NSHLAKRKPP MVVDDLFEDM KDGVKLLALL EVLSGQKLPC
EQGRRMKRIH AVANIGTALK FLEGRKSMHR GSPIKLVNIN STDIADGRPS IVLGLMWTII
LYFQIEELTS NLPQLQSLSS SASSVDSIVS SETPSPPSKR KVTTKIQGNA KKALLKWVQY
TAGKQTGIEV KDFGKSWRSG VAFHSVIHAI RPELVDLEKV KGRSNRENLE DAFTIAETEL
GIPRLLDPED VDVDKPDEKS IMTYVAQFLK HYPDIHNAGT DGQEDDEILP GFPSFAYSIQ
NFKREDRLIF KEMKVWIEQF ERDLTRAQIV ESNLQDKYQS FKHFRVQYEM KRKQIEHIIQ
PLHRDGKLSL DQALVKQSWD RVTSRLFDWH IQLDKSLPAP LGTIGAWLYR AEVALREEIT
IQQVHEETAN TIQRKLEQHK KIEAIRKEFP PAPTATSTHL CICARIRALH FCYYG
//
