ID A0A2I3HNZ1_NOMLE Unreviewed; 328 AA.
AC A0A2I3HNZ1;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Parvin alpha {ECO:0000313|Ensembl:ENSNLEP00000045343.1};
GN Name=PARVA {ECO:0000313|Ensembl:ENSNLEP00000045343.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000045343.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000045343.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000045343.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the parvin family.
CC {ECO:0000256|ARBA:ARBA00005666}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ADFV01112350; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01112351; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01112352; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01112353; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01112354; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01112355; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01112356; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01112357; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3HNZ1; -.
DR Ensembl; ENSNLET00000046666.1; ENSNLEP00000045343.1; ENSNLEG00000017668.2.
DR GeneTree; ENSGT00950000183194; -.
DR Proteomes; UP000001073; Chromosome 15.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR CDD; cd21335; CH_PARVA_rpt1; 1.
DR CDD; cd21337; CH_PARVA_rpt2; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR028433; Parvin.
DR PANTHER; PTHR12114:SF6; ALPHA-PARVIN; 1.
DR PANTHER; PTHR12114; PARVIN; 1.
DR Pfam; PF00307; CH; 2.
DR PIRSF; PIRSF039131; Parvin; 1.
DR SMART; SM00033; CH; 2.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR PROSITE; PS50021; CH; 2.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073}.
FT DOMAIN 51..158
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 218..325
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
SQ SEQUENCE 328 AA; 37553 MW; 6C91D88970BA15D6 CRC64;
LVSELQEEGM NAINLPLSPI PFELDPEDTM LEENEVRTMV DPNSRSDPKL QELMKVLIDW
INDVLVGERI IVKDLAEDLY DGQVLQKLFE KLESEKLNVA EVTQSEIAQK QKLQTVLEKI
NETLKLPPRS IKWNVDSVHA KSLVAILHLL VALSQYFRAP IRLPDHVSIQ VVVVQKREGI
LQSRQIQEEI TGNTEALSGR HERDAFDTLF DHAPDKLNVV KKTLITFVNK HLNKLNLEVT
ELETQFADGV YLVLLMGLLE GYFVPLHSFF LTPDSFEQKV LNVSFAFELM QDGGLEKPKP
RPEDIVNCDL KSTLRVLYNL FTKYRNVE
//
