ID A0A2I3HZL1_NOMLE Unreviewed; 349 AA.
AC A0A2I3HZL1;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500};
GN Name=WNT7B {ECO:0000313|Ensembl:ENSNLEP00000048936.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000048936.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000048936.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000048936.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Ligand for members of the frizzled family of seven
CC transmembrane receptors. {ECO:0000256|RuleBase:RU003500}.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|RuleBase:RU003500}.
CC -!- SIMILARITY: Belongs to the Wnt family. {ECO:0000256|ARBA:ARBA00005683,
CC ECO:0000256|RuleBase:RU003500}.
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DR EMBL; ADFV01129020; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01129021; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01129022; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01129023; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01129024; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01129025; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01129026; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01129027; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01129028; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01129029; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003281317.1; XM_003281269.3.
DR AlphaFoldDB; A0A2I3HZL1; -.
DR SMR; A0A2I3HZL1; -.
DR Ensembl; ENSNLET00000040662.1; ENSNLEP00000048936.1; ENSNLEG00000013688.2.
DR GeneTree; ENSGT00940000158861; -.
DR Proteomes; UP000001073; Chromosome 7b.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR GO; GO:0009888; P:tissue development; IEA:UniProt.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd19350; wnt_Wnt7b; 1.
DR Gene3D; 3.30.2460.20; -; 1.
DR InterPro; IPR005817; Wnt.
DR InterPro; IPR013300; Wnt7.
DR InterPro; IPR043158; Wnt_C.
DR InterPro; IPR018161; Wnt_CS.
DR PANTHER; PTHR12027:SF73; PROTEIN WNT-7B; 1.
DR PANTHER; PTHR12027; WNT RELATED; 1.
DR Pfam; PF00110; wnt; 1.
DR PRINTS; PR01891; WNT7PROTEIN.
DR PRINTS; PR01349; WNTPROTEIN.
DR SMART; SM00097; WNT1; 1.
DR PROSITE; PS00246; WNT1; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473,
KW ECO:0000256|RuleBase:RU003500};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687,
KW ECO:0000256|RuleBase:RU003500}.
SQ SEQUENCE 349 AA; 39327 MW; D114C329118C7CB1 CRC64;
MHRNFRKWIF YVFLCFGVLY VKLGALSSVV ALGANIICNK IPGLAPRQRA ICQSRPDAII
VIGEGAQMGI NECQYQFRFG RWNCSALGEK TVFGQELRVG SREAAFTYAI TAAGVAHAVT
AACSQGNLSN CGCDREKQGY YNQAEGWKWG GCSADVRYGI DFSRRFVDAR EIKKNARRLM
NLHNNEAGRK VLEDRMQLEC KCHGVSGSCT TKTCWTTLPK FREVGHLLKE KYNAAVQVEV
VRASRLRQPT FLRIKQLRSY QKPMETDLVY IEKSPNYCEE DAATGSVGTQ GRLCNRTSPG
ADGCDTMCCG RGYNTHQYTK VWQCNCKFHW CCFVKCNTCS ERTEVFTCK
//
