ID A0A2I3HZY9_NOMLE Unreviewed; 329 AA.
AC A0A2I3HZY9;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=GRAM domain containing 2B {ECO:0000313|Ensembl:ENSNLEP00000049066.1};
GN Name=GRAMD2B {ECO:0000313|Ensembl:ENSNLEP00000049066.1};
OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Nomascus.
OX NCBI_TaxID=61853 {ECO:0000313|Ensembl:ENSNLEP00000049066.1, ECO:0000313|Proteomes:UP000001073};
RN [1] {ECO:0000313|Ensembl:ENSNLEP00000049066.1, ECO:0000313|Proteomes:UP000001073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Gibbon Genome Sequencing Consortium;
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSNLEP00000049066.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; ADFV01188147; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01188148; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01188149; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01188150; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01188151; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01188152; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01188153; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADFV01188154; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3HZY9; -.
DR Ensembl; ENSNLET00000059923.1; ENSNLEP00000049066.1; ENSNLEG00000012129.3.
DR GeneTree; ENSGT00940000156980; -.
DR Proteomes; UP000001073; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd13220; PH-GRAM_GRAMDC; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR46645:SF2; GRAM DOMAIN-CONTAINING PROTEIN 2B; 1.
DR PANTHER; PTHR46645; GRAM DOMAIN-CONTAINING PROTEIN 2B-RELATED; 1.
DR Pfam; PF02893; GRAM; 1.
DR SMART; SM00568; GRAM; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001073};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 239..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..74
FT /note="GRAM"
FT /evidence="ECO:0000259|SMART:SM00568"
FT REGION 117..136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 161..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 117..134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 329 AA; 36617 MW; C1DC0E800E3E369B CRC64;
MLYKANMHFH KLFLSVPTEE PLKQSFTCAL QKEILYQGKL FVSENWICFH SKVFGKDTKI
SIPAFSVTLI KKTKTALLVP NALIIATVTD RYIFVSLLSR DSTYKLLKSV CGHLENTSVG
NSPNPSSAEN SFRADRPSSL PLDFNDEFSD LDGVVQQRRQ DLEGYSSSGS QTPESENSRD
FHVTESQTVL NVSKGEAKPT RADAHVNRVP EGKAKSLPAQ GLSETVGILH KVKSQKCPML
HHILIFYAIV ACALIISTFY MRYRINTLEE QLGLLTSIVD THNTEQAAPS GLGSQVQFNV
EVLCQELTAN IVKLEKIQNN LQKLLENGD
//
