ID A0A2I3LLN2_PAPAN Unreviewed; 2965 AA.
AC A0A2I3LLN2;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 2.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Bromodomain PHD finger transcription factor {ECO:0000313|Ensembl:ENSPANP00000024362.2};
GN Name=BPTF {ECO:0000313|Ensembl:ENSPANP00000024362.2};
OS Papio anubis (Olive baboon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Papio.
OX NCBI_TaxID=9555 {ECO:0000313|Ensembl:ENSPANP00000024362.2, ECO:0000313|Proteomes:UP000028761};
RN [1] {ECO:0000313|Ensembl:ENSPANP00000024362.2, ECO:0000313|Proteomes:UP000028761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Liu Y.L., Abraham K.A., Akbar H.A., Ali S.A., Anosike U.A., Aqrawi P.A.,
RA Arias F.A., Attaway T.A., Awwad R.A., Babu C.B., Bandaranaike D.B.,
RA Battles P.B., Bell A.B., Beltran B.B., Berhane-Mersha D.B., Bess C.B.,
RA Bickham C.B., Bolden T.B., Carter K.C., Chau D.C., Chavez A.C.,
RA Clerc-Blankenburg K.C., Coyle M.C., Dao M.D., Davila M.L.D.,
RA Davy-Carroll L.D., Denson S.D., Dinh H.D., Fernandez S.F., Fernando P.F.,
RA Forbes L.F., Francis C.F., Francisco L.F., Fu Q.F., Garcia-Iii R.G.,
RA Garrett T.G., Gross S.G., Gubbala S.G., Hirani K.H., Hogues M.H.,
RA Hollins B.H., Jackson L.J., Javaid M.J., Jhangiani S.J., Johnson A.J.,
RA Johnson B.J., Jones J.J., Joshi V.J., Kalu J.K., Khan N.K., Korchina V.K.,
RA Kovar C.K., Lago L.L., Lara F.L., Le T.-K.L., Lee S.L., Legall-Iii F.L.,
RA Lemon S.L., Liu J.L., Liu Y.-S.L., Liyanage D.L., Lopez J.L.,
RA Lorensuhewa L.L., Mata R.M., Mathew T.M., Mercado C.M., Mercado I.M.,
RA Morales K.M., Morgan M.M., Munidasa M.M., Ngo D.N., Nguyen L.N.,
RA Nguyen T.N., Nguyen N.N., Obregon M.O., Okwuonu G.O., Ongeri F.O.,
RA Onwere C.O., Osifeso I.O., Parra A.P., Patil S.P., Perez A.P., Perez Y.P.,
RA Pham C.P., Pu L.-L.P., Puazo M.P., Quiroz J.Q., Rouhana J.R., Ruiz M.R.,
RA Ruiz S.-J.R., Saada N.S., Santibanez J.S., Scheel M.S., Schneider B.S.,
RA Simmons D.S., Sisson I.S., Tang L.-Y.T., Thornton R.T., Tisius J.T.,
RA Toledanes G.T., Trejos Z.T., Usmani K.U., Varghese R.V., Vattathil S.V.,
RA Vee V.V., Walker D.W., Weissenberger G.W., White C.W., Williams A.W.,
RA Woodworth J.W., Wright R.W., Zhu Y.Z., Han Y.H., Newsham I.N.,
RA Nazareth L.N., Worley K.W., Muzny D.M., Rogers J.R., Gibbs R.G.;
RT "Whole Genome Assembly of Papio anubis.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPANP00000024362.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR STRING; 9555.ENSPANP00000024362; -.
DR Ensembl; ENSPANT00000032291.2; ENSPANP00000024362.2; ENSPANG00000020520.3.
DR GeneTree; ENSGT00940000154830; -.
DR Proteomes; UP000028761; Chromosome 17.
DR Bgee; ENSPANG00000020520; Expressed in postnatal subventricular zone and 68 other cell types or tissues.
DR ExpressionAtlas; A0A2I3LLN2; baseline.
DR GO; GO:0016589; C:NURF complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd05509; Bromo_gcn5_like; 1.
DR CDD; cd15559; PHD1_BPTF; 1.
DR CDD; cd15560; PHD2_3_BPTF; 2.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 3.
DR InterPro; IPR038028; BPTF.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR018501; DDT_dom.
DR InterPro; IPR028941; WHIM2_dom.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45975; NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF; 1.
DR PANTHER; PTHR45975:SF2; NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF02791; DDT; 1.
DR Pfam; PF00628; PHD; 3.
DR Pfam; PF15613; WSD; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00571; DDT; 1.
DR SMART; SM00249; PHD; 3.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 3.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS50827; DDT; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 3.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000028761};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 101..161
FT /note="DDT"
FT /evidence="ECO:0000259|PROSITE:PS50827"
FT DOMAIN 251..298
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 2728..2779
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 2786..2837
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 2863..2933
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 1..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 428..610
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 617..636
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 842..861
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 915..1018
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1075..1203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1234..1292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1369..1397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1464..1562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1834..1864
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2021..2041
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2094..2130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2207..2410
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2575..2594
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2657..2719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1884..1911
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2481..2511
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..48
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 52..66
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 75..90
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 428..487
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 488..532
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 549..587
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 588..602
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 924..1014
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1078..1099
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1105..1148
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1158..1178
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1234..1254
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1268..1292
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1369..1387
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1469..1521
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1528..1561
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2207..2267
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2274..2410
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2575..2591
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2658..2682
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2695..2719
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2965 AA; 330683 MW; 239CBDB5E0335CFB CRC64;
MVSEEEEEED GDAEETQDSE DDEEDEMEED DDDSDYPEEM EDDDDDASYC TESSFRSHST
YSSTPGRRKP RVHRPRSPIL EEKDIPPLEF PKSSEDLMVP NEHIMNVIAI YEVLRNFGTV
LRLSPFRFED FCAALVSQEQ CTLMAEMHVV LLKAVLREED TSNTTFGPAD LKDSVNSTLY
FIDGMTWPEV LRVYCESDKE YHHVLPYQEA EDYPYGPVEN KIKVLQFLVD QFLTTNIARE
ELMSEGVIQY DDHCRVCHKL GDLLCCETCS AVYHLECVKP PLEEVPEDEW QCEVCVAHKV
PGVTDCVAEI QKNKPYIRHE PIGYDRSRRK YWFLNRRLII EEDTENENEK KIWYYSTKVQ
LAELIDCLDK DYWEAELCKI LEEMREEIHR HMDITEDLTN KARGSNKSFL AAANEEILES
IRVKKGDIDN VKSPEETEKD KNETENDSKD AEKSREEFED QSLEKDSDDK TPDDDPEQGK
SEEPTEVGDK GNSVSANLGD NTTNASSEET SPSEGRSPVG CLSETPDSSN MAEKKVASEL
PQDVPEEPNK ICESSNTSAT TTSIQPNLEN SNSSSELNSS QSESAKAADD PENGERESHT
PVSIQEEIVG DFKLEKSNGE LSESPGAGKG SSGSTRIITR LRNPDSKLSQ LKSQQVAAAA
HEANKLFKEG KEVLVVNSQG EISRLSTKKE VVMKGNINNY FKLGQEGKYR VYHNQYSTNS
FALNKHQHRE DHDKRRHLAH KFCLTPAGEF KWNGSVHGSK VLTISTLRLT ITQLENNIPS
SFLHPNWASH RANWIKAVQM CSKPREFALA LAILECAVKP VVMLPIWRES LGHTRLHRMT
SIEREEKEKV KKKEKKQEEE ETMQQATWVK YTFPVKHQVW KQKGEEYRVT GYGGWSWISK
THVYRFVPKL PGNTNVNYRK SLEGTKNNMD ENMDESDKRK CSRSPKKIKT EPDSEKDEVK
DSDAAKGADQ SEMDISKITE KKDQDVKELL DSDSDKPCKE EPMEIDDDMK TESHVNCQES
SQVDVVNVSE GFHLRTSYKK KTKSSKLDGL LERRIKQFTL EEKQRLEKIK LEGGIKGIGK
TSTNSSKNLS ESPVITKAKE GCQSDSMRQE QSPNANNDRP EDLIQGCSES DSSVLGMSDP
SHTTNKLYPK DQVLDDVSFR SPETNCQKQN SVENDIEENV SDPASKGQEP SKSRTKGNDI
FIDDSKLANA GDIGSLIYRN KKLLIQEEND TIVSSSKSAL HSSVPKSTND RDATPLSKAM
DFEGKLGCDS ESNSTLENSS DTVSVHDSSE EDMIVQNSNE SISEQFRTQE QGIEGLEPLK
CELVSDKSTG NCEDRLLGKV TEANGKKTSQ QKKLEERSVN KCSDQIKLKN TTDKKNNENR
ESEKKGQRTS TFQINGKDNK PKIYLKGECL KEISESKVVS GNVEPKVNNI NKIIPENDIK
SLTVKESAVR PFINGDVIME DFNERNSSET KSHLLSSSDA EGNYRDSLET LPSTKESDGT
QTTTPSPSCP ESNSVNQVED MEIETSEVKK VSSSPVTSGE ESNLSNDFID ENGLPVNKNE
NVNGESKRKT VITEVTTMTS TVATESKTVI KVEKGDKQTV VSSTENCAKS TVTTTTTTVT
KLSTPSTGSS VDIISVKEQS KTVVTTTVTD SLTTTGGTLV TSMTVSKEYS TRDKVKLMKF
SRPKKTRSGT ALPSYRKFVT KSSKKSIFVL PNDDLKKLAR KGGIREVPYF NYNAKPALDI
WPYPSPRPTF GITWRYRLQT VKSLAGVSLM LRLLWASLRW DDMAAKAPPG GGTTRTETSE
TEITTTEIIK RRDVGPYGIR SEYCIRKIIC PIGVPETPKE TPTPQRKGLR SSALRPKRPE
TPKQTGPVII ETWVAEEELE LWEIRAFAER VEKEKAQAVE QQAKKRLEQQ KPTVIATSTT
SPTNSTTSTI SPAQKVMVAP ISGSVTTGTK MVLTTKVGSP ATVTFQQNKN FHQTFATWVK
QGQSNSGVVQ VQQKVLGIIP SSTGTSQQTF TSFQPRTATV TIRPNTSGSG GTTSNSQVIT
GPQIRPGMTV IRTPLQQSTL GKAIIRTPVM VQPGAPQQVM TQIIRGQPVS TAISAPNTVS
STPGQKSLTS ATSTSNIQSS ASQPPRPQQG QVKLTMAQLT QLTQGHGGNQ GLTVVIQGQG
QTTGQLQLIP QGVTVLPGPG QQLMQAAMPN GTVQRFLFTP LATTATTAST TTTTVSTTAA
GTGEQRQSKL SPQTQVHQDK TLPPAQSSSV GPAEAQPQTA QPSAQPQPQT QPQSPAQPEV
QTQPEVQTQT TVSSHVPSEA QPTQAQSSKP QVAAQSQPQS NVQGQSPVRV QSPSQTRIRP
STPSQLSPGQ QSQVQTTTSQ PIPIQPHTSL QIPSQGQPQS QPQVQSSTQT LSSGQTLNQV
TVSSPSRPQL QIQQPQPQVI AVPQLQQQVQ VLSQIQSQVV AQIQAQQSGV PQQIKLQLPI
QIQQSNAVQT HQIQNVVTVQ AASVQEQLQR VQQLRDQQQK KKQQQIEIKR EHTLQASNQS
EIIQKQVVMK HNAVIEHLKQ KKSMTPAERE ENQRMIVCNQ VMKYILDKID KEEKQAAKKR
KREESVEQKR SKQNATKLSA LLFKHKEQLR AEILKKRALL DKDLQIEVQE ELKRDLKIKK
EKDLMQVAQS TAVAVPCPPV TAAPPAPPAP PPSPPPPPAV QHTGLLSTPT LPAASQKRKR
EEEKDSSSKS KKKKMISTTS KETKKDTKLY CICKTPYDES KFYIGCDLCT NWYHGECVGI
TEKEAKKMDV YICNDCKRAQ EGSSEELYCI CRTPYDESQF YIGCDRCQNW YHGRCVGILQ
SEAELIDEYV CPQCQSTEDA MTVLTPLTEK DYEGLKRVLR SLQAHKMAWP FLEPVDPNDA
PDYYGVIKEP MDLATMEERV QRRYYEKLTE FVADMTKIFD NCRYYNPSDS PFYQCAEVLE
SFFVQKLKGF KASRSHNNKL QSTAS
//
