GenomeNet

Database: UniProt
Entry: A0A2I3LQ33_PAPAN
LinkDB: A0A2I3LQ33_PAPAN
Original site: A0A2I3LQ33_PAPAN 
ID   A0A2I3LQ33_PAPAN        Unreviewed;      1012 AA.
AC   A0A2I3LQ33;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   13-FEB-2019, entry version 6.
DE   SubName: Full=Ryanodine receptor 2 {ECO:0000313|Ensembl:ENSPANP00000025591};
GN   Name=RYR2 {ECO:0000313|Ensembl:ENSPANP00000025591};
OS   Papio anubis (Olive baboon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Cercopithecidae; Cercopithecinae; Papio.
OX   NCBI_TaxID=9555 {ECO:0000313|Ensembl:ENSPANP00000025591, ECO:0000313|Proteomes:UP000028761};
RN   [1] {ECO:0000313|Ensembl:ENSPANP00000025591, ECO:0000313|Proteomes:UP000028761}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Liu Y.L., Abraham K.A., Akbar H.A., Ali S.A., Anosike U.A.,
RA   Aqrawi P.A., Arias F.A., Attaway T.A., Awwad R.A., Babu C.B.,
RA   Bandaranaike D.B., Battles P.B., Bell A.B., Beltran B.B.,
RA   Berhane-Mersha D.B., Bess C.B., Bickham C.B., Bolden T.B.,
RA   Carter K.C., Chau D.C., Chavez A.C., Clerc-Blankenburg K.C.,
RA   Coyle M.C., Dao M.D., Davila M.L.D., Davy-Carroll L.D., Denson S.D.,
RA   Dinh H.D., Fernandez S.F., Fernando P.F., Forbes L.F., Francis C.F.,
RA   Francisco L.F., Fu Q.F., Garcia-Iii R.G., Garrett T.G., Gross S.G.,
RA   Gubbala S.G., Hirani K.H., Hogues M.H., Hollins B.H., Jackson L.J.,
RA   Javaid M.J., Jhangiani S.J., Johnson A.J., Johnson B.J., Jones J.J.,
RA   Joshi V.J., Kalu J.K., Khan N.K., Korchina V.K., Kovar C.K.,
RA   Lago L.L., Lara F.L., Le T.-K.L., Lee S.L., Legall-Iii F.L.,
RA   Lemon S.L., Liu J.L., Liu Y.-S.L., Liyanage D.L., Lopez J.L.,
RA   Lorensuhewa L.L., Mata R.M., Mathew T.M., Mercado C.M., Mercado I.M.,
RA   Morales K.M., Morgan M.M., Munidasa M.M., Ngo D.N., Nguyen L.N.,
RA   Nguyen T.N., Nguyen N.N., Obregon M.O., Okwuonu G.O., Ongeri F.O.,
RA   Onwere C.O., Osifeso I.O., Parra A.P., Patil S.P., Perez A.P.,
RA   Perez Y.P., Pham C.P., Pu L.-L.P., Puazo M.P., Quiroz J.Q.,
RA   Rouhana J.R., Ruiz M.R., Ruiz S.-J.R., Saada N.S., Santibanez J.S.,
RA   Scheel M.S., Schneider B.S., Simmons D.S., Sisson I.S., Tang L.-Y.T.,
RA   Thornton R.T., Tisius J.T., Toledanes G.T., Trejos Z.T., Usmani K.U.,
RA   Varghese R.V., Vattathil S.V., Vee V.V., Walker D.W.,
RA   Weissenberger G.W., White C.W., Williams A.W., Woodworth J.W.,
RA   Wright R.W., Zhu Y.Z., Han Y.H., Newsham I.N., Nazareth L.N.,
RA   Worley K.W., Muzny D.M., Rogers J.R., Gibbs R.G.;
RT   "Whole Genome Assembly of Papio anubis.";
RL   Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSPANP00000025591}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2018) to UniProtKB.
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DR   EMBL; AHZZ02017986; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AHZZ02017987; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSPANT00000038096; ENSPANP00000025591; ENSPANG00000024680.
DR   GeneTree; ENSGT00940000154906; -.
DR   Proteomes; UP000028761; Chromosome 1.
DR   ExpressionAtlas; A0A2I3LQ33; baseline.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd12877; SPRY1_RyR; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   InterPro; IPR035761; SPRY1_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF01365; RYDR_ITPR; 1.
DR   Pfam; PF02026; RyR; 2.
DR   Pfam; PF00622; SPRY; 1.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 1.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF49899; SSF49899; 1.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 1.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000028761};
KW   Reference proteome {ECO:0000313|Proteomes:UP000028761};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904}.
FT   DOMAIN       91    146       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      153    198       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      206    261       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      267    324       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      332    389       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      580    790       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   COILED      453    473       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1012 AA;  113295 MW;  0264150926EBE7D1 CRC64;
     EAEAGESLED DEVVLQCTAT IHKEQQKLCL AAEGFGNRLC FLESTSNSKN VPPDLSICTF
     VLEQSLSVRA LQEMLANTVE KSEGTAQGGG HRTLLYGHAI LLRHSYSGMY LCCLSTSRSS
     TDKLAFDVGL QEDTTGEACW WTIHPASKQR SEGEKVRVGD DLILVSVSSE RYLHLSYGNG
     SLHVDAAFQQ TLWSVAPISS GSEAAQGYLI GGDVLRLLHG HMDECLTVPS GEHGEEQRRT
     VHYEGGAVSV HARSLWRLET LRVAWSGSHI RWGQPFRLRH VTTGKYLSLM EDKNLLLMDK
     EKADVKSTAF TFRSSKEKLD VGVRKEVDGM GTSEIKYGDS VCYIQHVDTG LWLTYQSVDV
     KSVRMGSIQR KAIMHHEGHM DDGISLSRSQ HEESRTARVI RSTVFLFNRF IRGLDALSKK
     AKASTVDLPI ESVSLSLQDL IGYFHPPDEH LEHEDKQNRL RALKNRQNLF QEEGMINLVL
     ECIDRLHVYS SAAHFADVAG REAGESWKSI LNSLYELLAA LIRGNRKNCA QFSGSLDWLI
     SRLERLEASS GILEVLHCVL VESPEALNII KEGHIKSIIS LLDKHGRNHK VLDVLCSLCV
     CHGVAVRSNQ HLICDNLLPG RDLLLQTRLV NHVSSMRPNI FLGVSEGSAQ YKKWYYELMV
     DHTEPFVTAE ATHLRVGWAS TEGYSPYPGG GEEWGGNGVG DDLFSYGFDG LHLWSGCIAR
     TVSSPNQHLL RTDDVISCCL DLSAPSISFR INGQPVQGMF ENFNIDGLFF PVVSFSAGIK
     VRFLLGGRHG EFKFLPPPGY APCYEAVLPK EKLKVEHSRE YKQERTYTRD LLGPTVSLTQ
     AAFTPIPVDT SQIVLPPHLE RIREKLAENI HELWVMNKIE LGWQYGPVRD DNKRQHPCLV
     EFSKLPEQER NYNLQMSLET LKTLLALGCH VGISDEHAED KVKKMKLPKN YQLTSGYKPA
     PMDLSFIKLT PSQEAMVDKL AENAHNVWAR DRIRQGWTYG IQQVRGNETL GG
//
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