ID A0A2I3LZG5_PAPAN Unreviewed; 1310 AA.
AC A0A2I3LZG5;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 2.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Cadherin domain-containing protein {ECO:0000259|PROSITE:PS50268};
OS Papio anubis (Olive baboon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Papio.
OX NCBI_TaxID=9555 {ECO:0000313|Ensembl:ENSPANP00000028863.2, ECO:0000313|Proteomes:UP000028761};
RN [1] {ECO:0000313|Ensembl:ENSPANP00000028863.2, ECO:0000313|Proteomes:UP000028761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Liu Y.L., Abraham K.A., Akbar H.A., Ali S.A., Anosike U.A., Aqrawi P.A.,
RA Arias F.A., Attaway T.A., Awwad R.A., Babu C.B., Bandaranaike D.B.,
RA Battles P.B., Bell A.B., Beltran B.B., Berhane-Mersha D.B., Bess C.B.,
RA Bickham C.B., Bolden T.B., Carter K.C., Chau D.C., Chavez A.C.,
RA Clerc-Blankenburg K.C., Coyle M.C., Dao M.D., Davila M.L.D.,
RA Davy-Carroll L.D., Denson S.D., Dinh H.D., Fernandez S.F., Fernando P.F.,
RA Forbes L.F., Francis C.F., Francisco L.F., Fu Q.F., Garcia-Iii R.G.,
RA Garrett T.G., Gross S.G., Gubbala S.G., Hirani K.H., Hogues M.H.,
RA Hollins B.H., Jackson L.J., Javaid M.J., Jhangiani S.J., Johnson A.J.,
RA Johnson B.J., Jones J.J., Joshi V.J., Kalu J.K., Khan N.K., Korchina V.K.,
RA Kovar C.K., Lago L.L., Lara F.L., Le T.-K.L., Lee S.L., Legall-Iii F.L.,
RA Lemon S.L., Liu J.L., Liu Y.-S.L., Liyanage D.L., Lopez J.L.,
RA Lorensuhewa L.L., Mata R.M., Mathew T.M., Mercado C.M., Mercado I.M.,
RA Morales K.M., Morgan M.M., Munidasa M.M., Ngo D.N., Nguyen L.N.,
RA Nguyen T.N., Nguyen N.N., Obregon M.O., Okwuonu G.O., Ongeri F.O.,
RA Onwere C.O., Osifeso I.O., Parra A.P., Patil S.P., Perez A.P., Perez Y.P.,
RA Pham C.P., Pu L.-L.P., Puazo M.P., Quiroz J.Q., Rouhana J.R., Ruiz M.R.,
RA Ruiz S.-J.R., Saada N.S., Santibanez J.S., Scheel M.S., Schneider B.S.,
RA Simmons D.S., Sisson I.S., Tang L.-Y.T., Thornton R.T., Tisius J.T.,
RA Toledanes G.T., Trejos Z.T., Usmani K.U., Varghese R.V., Vattathil S.V.,
RA Vee V.V., Walker D.W., Weissenberger G.W., White C.W., Williams A.W.,
RA Woodworth J.W., Wright R.W., Zhu Y.Z., Han Y.H., Newsham I.N.,
RA Nazareth L.N., Worley K.W., Muzny D.M., Rogers J.R., Gibbs R.G.;
RT "Whole Genome Assembly of Papio anubis.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPANP00000028863.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Potential calcium-dependent cell-adhesion protein.
CC {ECO:0000256|ARBA:ARBA00037723}.
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DR Ensembl; ENSPANT00000039236.2; ENSPANP00000028863.2; ENSPANG00000010796.3.
DR GeneTree; ENSGT00940000158335; -.
DR Proteomes; UP000028761; Chromosome X.
DR Bgee; ENSPANG00000010796; Expressed in postnatal subventricular zone and 36 other cell types or tissues.
DR ExpressionAtlas; A0A2I3LZG5; baseline.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 6.
DR Gene3D; 2.60.40.60; Cadherins; 7.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013164; Cadherin_N.
DR InterPro; IPR013585; Protocadherin.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR PANTHER; PTHR24028:SF254; PROTOCADHERIN-11 X-LINKED-RELATED; 1.
DR Pfam; PF00028; Cadherin; 6.
DR Pfam; PF08266; Cadherin_2; 1.
DR Pfam; PF08374; Protocadherin; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 6.
DR SUPFAM; SSF49313; Cadherin-like; 6.
DR PROSITE; PS00232; CADHERIN_1; 4.
DR PROSITE; PS50268; CADHERIN_2; 7.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Reference proteome {ECO:0000313|Proteomes:UP000028761};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..1310
FT /note="Cadherin domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5035283471"
FT DOMAIN 22..139
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 140..249
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 250..355
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 362..466
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 467..570
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 571..673
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 685..795
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT REGION 1021..1073
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1288..1310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1310 AA; 143343 MW; 18AA65652A4E097A CRC64;
MDLLSGTYIF AVLLACVVFH SGAQEKNYTI REEMPENVLI GDLLKDLDLS LVPNKSLTSA
MQFKLVYKTG DVPLIRIEED TGEIFTTGAR IDREKLCVGI PTDEQCFYEV EVAILPDEIF
RLVKIRFLIE DINDNAPLFP TTVINISIPE NSAINSKYTL PAAIDPDVGI NGVQNYELIK
GQNIFGLDVI ETPEGEKMPQ LIVQKELDRE EKDTYVMKVK VEDGGFPQRS STAILQVSVT
DTNDNHPVFK ETEIEVSIPE NAPVGTSVTQ LHATDADIGE NARIHFSFSN LVSNIAKRLF
HLNTTTGLIT IKEPLDREET PNHKLLVLAS DGGLVPARAM VLVNVTDVND NVPSIDIRYI
VNTINDTVVL SENIPLNTKI ALITVTDKDA DHNGRVTCFT DHEIPFRLRP VFSNQFLLET
AAYLDYESTK EYAIKLLAAD AGKPPLNQSA MLFIKVKDEN DNAPVFTQSL VTVSIPENNS
PGIQLTKVSA TDADTGPNAE INYLLGPDAP PEFSLDRRTG MLTVVKKLDR EKEEKYFFTV
LAKDNGVPPL TSNVTVFVSV IDQNDNTPTF THNEYNFYVP ENLPKHGTVG LITVTDPDYG
ENSAVTLSIL DENDGFTIDS QTGVIRPNIS FDREKQESYT FYVKAEDGGR VSRSSSAKVT
INVVDVNDNK PVFIVPPSNY SYELVLPSTD PGTVVFQVIA VDNDTGMNAE VRYSIVGENT
RDLFEINETT GNIIMKEKCD VTDLGLHRVL VKANDLGQPD SLFSVVTVNL FVNESVTNAT
LINELLHKST EAPVTPNTEI ADASSPTIDY VKILVAVVAG TITVVVVIFI TAVVRCRQAP
HLKAAQKNKQ NSEWATPNPE NRQMIMMKKK KKKKKHPPKN LLLNFVTIEE TKADDVDNDG
NSITLELPID LEEQTMGKYN WVTTPTTFKP DSPDLARHYK SASPQPAFQI QPETPLNSKH
HIIQELPLDN TFVACDSISK CSSSSSDPYS VSDSGYPMTT FEAPVSVHAR PSQRRVTFHL
PEGSQESGSD GGLGDQDAGS LTSASHGLPL GYPQEEYFDH VTPNNRTEGD GNSDPECTFI
PGLKKAAEIT VQPTVEEASD NCTQECLIYG HSDACWMPAS LNDSSSSQAQ ASALCHSPPL
SQASTHHHSP PVTQTIALCH SPPVTQTIAL CHSPPPIQIS ALHHSPPLAQ ATALRHSPPS
AQASALCYSP PLAQAAAICH SSPLPQVTAL HRSQAQSSVS LQQGWVQGAD GLCSVDQGVQ
GSATSQFYTM SERLHPSDDS IKVIPLTTFT PRQQARPSKG DSPIMEEHPL
//
