ID A0A2I3MX78_PAPAN Unreviewed; 639 AA.
AC A0A2I3MX78;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 2.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=GRAM domain containing 4 {ECO:0000313|Ensembl:ENSPANP00000040216.2};
GN Name=GRAMD4 {ECO:0000313|Ensembl:ENSPANP00000040216.2};
OS Papio anubis (Olive baboon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Papio.
OX NCBI_TaxID=9555 {ECO:0000313|Ensembl:ENSPANP00000040216.2, ECO:0000313|Proteomes:UP000028761};
RN [1] {ECO:0000313|Ensembl:ENSPANP00000040216.2, ECO:0000313|Proteomes:UP000028761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Liu Y.L., Abraham K.A., Akbar H.A., Ali S.A., Anosike U.A., Aqrawi P.A.,
RA Arias F.A., Attaway T.A., Awwad R.A., Babu C.B., Bandaranaike D.B.,
RA Battles P.B., Bell A.B., Beltran B.B., Berhane-Mersha D.B., Bess C.B.,
RA Bickham C.B., Bolden T.B., Carter K.C., Chau D.C., Chavez A.C.,
RA Clerc-Blankenburg K.C., Coyle M.C., Dao M.D., Davila M.L.D.,
RA Davy-Carroll L.D., Denson S.D., Dinh H.D., Fernandez S.F., Fernando P.F.,
RA Forbes L.F., Francis C.F., Francisco L.F., Fu Q.F., Garcia-Iii R.G.,
RA Garrett T.G., Gross S.G., Gubbala S.G., Hirani K.H., Hogues M.H.,
RA Hollins B.H., Jackson L.J., Javaid M.J., Jhangiani S.J., Johnson A.J.,
RA Johnson B.J., Jones J.J., Joshi V.J., Kalu J.K., Khan N.K., Korchina V.K.,
RA Kovar C.K., Lago L.L., Lara F.L., Le T.-K.L., Lee S.L., Legall-Iii F.L.,
RA Lemon S.L., Liu J.L., Liu Y.-S.L., Liyanage D.L., Lopez J.L.,
RA Lorensuhewa L.L., Mata R.M., Mathew T.M., Mercado C.M., Mercado I.M.,
RA Morales K.M., Morgan M.M., Munidasa M.M., Ngo D.N., Nguyen L.N.,
RA Nguyen T.N., Nguyen N.N., Obregon M.O., Okwuonu G.O., Ongeri F.O.,
RA Onwere C.O., Osifeso I.O., Parra A.P., Patil S.P., Perez A.P., Perez Y.P.,
RA Pham C.P., Pu L.-L.P., Puazo M.P., Quiroz J.Q., Rouhana J.R., Ruiz M.R.,
RA Ruiz S.-J.R., Saada N.S., Santibanez J.S., Scheel M.S., Schneider B.S.,
RA Simmons D.S., Sisson I.S., Tang L.-Y.T., Thornton R.T., Tisius J.T.,
RA Toledanes G.T., Trejos Z.T., Usmani K.U., Varghese R.V., Vattathil S.V.,
RA Vee V.V., Walker D.W., Weissenberger G.W., White C.W., Williams A.W.,
RA Woodworth J.W., Wright R.W., Zhu Y.Z., Han Y.H., Newsham I.N.,
RA Nazareth L.N., Worley K.W., Muzny D.M., Rogers J.R., Gibbs R.G.;
RT "Whole Genome Assembly of Papio anubis.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPANP00000040216.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A2I3MX78; -.
DR STRING; 9555.ENSPANP00000040216; -.
DR Ensembl; ENSPANT00000034500.2; ENSPANP00000040216.2; ENSPANG00000009200.3.
DR GeneTree; ENSGT00390000010968; -.
DR OMA; XYLCFES; -.
DR Proteomes; UP000028761; Chromosome 16.
DR Bgee; ENSPANG00000009200; Expressed in cornea and 64 other cell types or tissues.
DR ExpressionAtlas; A0A2I3MX78; baseline.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
DR GO; GO:0006915; P:apoptotic process; IEA:InterPro.
DR GO; GO:0034164; P:negative regulation of toll-like receptor 9 signaling pathway; IEA:Ensembl.
DR CDD; cd13221; PH-GRAM_GRAMDC4; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR037847; GRAMDC4.
DR InterPro; IPR037845; GRAMDC4_PH-GRAM.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR37402; GRAM DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR37402:SF1; GRAM DOMAIN-CONTAINING PROTEIN 4; 1.
DR Pfam; PF02893; GRAM; 1.
DR SMART; SM00568; GRAM; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028761};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 307..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 506..584
FT /note="GRAM"
FT /evidence="ECO:0000259|SMART:SM00568"
FT REGION 85..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 196..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 476..496
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 145..195
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 639 AA; 73419 MW; 697F292332868295 CRC64;
MQLFTYPCGF VDTHLTRWVS AECRYFVCSL VPVLAVGFPG RTPSREPERH VRVKQRSSVL
NMLRRLDKIR FRGHKRDDFL DLAESPNASD TECSDEIPLK VPRTSPRDSE ELRDPAGPGT
LIMATGVQDF NRTEFDRLNE IKGHLEIALL EKHFLQEELR KLREETNAEM LRQELDRERQ
RRMELEQKVQ EVLKARTEEQ TAQQPPKGQA QASNGAERRS QGLSSRLQKW FYERFGEYVE
DFRFQPEENT VETEEPLSAR RLTENMRRLK RGAKPVTNFV KNLSALSDWY SVYTSAIAFT
VYMNAVWHGW AIPLFLFLAI LRLSLNYLIA RGWRIQWSIV PEVSEPMEPP KEDLTVSEKF
QLVLDVAQKA QNLFGKMADI LEKIKNLFMW VQPEITQKLY VALWAAFLAS CFFPYRLVGL
TVGLYAGIKF FLIDFIFKRC PRLRAKYDTP YIIWKSLPTD PQLKERSSAA VSRRLQTTSS
RSYVPSAPAG LGKEEDAGRF HSTKKGNFHE IFNLTENERP LAVCENGWRC CLINRDRKMP
TDYIRNGVLY VTENYLCFES SKSGSSKRNK VIKLVDITDI QKYKVLSVLP GSGMGIAVST
PSTQKPLVFG AMVHRDEAFE TILSQYIKIT SAAASGGDS
//
