ID A0A2I3N1D0_PAPAN Unreviewed; 990 AA.
AC A0A2I3N1D0;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 25-MAY-2022, sequence version 2.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Leucine rich repeats and immunoglobulin like domains 1 {ECO:0000313|Ensembl:ENSPANP00000041804.2};
GN Name=LRIG1 {ECO:0000313|Ensembl:ENSPANP00000041804.2};
OS Papio anubis (Olive baboon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Papio.
OX NCBI_TaxID=9555 {ECO:0000313|Ensembl:ENSPANP00000041804.2, ECO:0000313|Proteomes:UP000028761};
RN [1] {ECO:0000313|Ensembl:ENSPANP00000041804.2, ECO:0000313|Proteomes:UP000028761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Liu Y.L., Abraham K.A., Akbar H.A., Ali S.A., Anosike U.A., Aqrawi P.A.,
RA Arias F.A., Attaway T.A., Awwad R.A., Babu C.B., Bandaranaike D.B.,
RA Battles P.B., Bell A.B., Beltran B.B., Berhane-Mersha D.B., Bess C.B.,
RA Bickham C.B., Bolden T.B., Carter K.C., Chau D.C., Chavez A.C.,
RA Clerc-Blankenburg K.C., Coyle M.C., Dao M.D., Davila M.L.D.,
RA Davy-Carroll L.D., Denson S.D., Dinh H.D., Fernandez S.F., Fernando P.F.,
RA Forbes L.F., Francis C.F., Francisco L.F., Fu Q.F., Garcia-Iii R.G.,
RA Garrett T.G., Gross S.G., Gubbala S.G., Hirani K.H., Hogues M.H.,
RA Hollins B.H., Jackson L.J., Javaid M.J., Jhangiani S.J., Johnson A.J.,
RA Johnson B.J., Jones J.J., Joshi V.J., Kalu J.K., Khan N.K., Korchina V.K.,
RA Kovar C.K., Lago L.L., Lara F.L., Le T.-K.L., Lee S.L., Legall-Iii F.L.,
RA Lemon S.L., Liu J.L., Liu Y.-S.L., Liyanage D.L., Lopez J.L.,
RA Lorensuhewa L.L., Mata R.M., Mathew T.M., Mercado C.M., Mercado I.M.,
RA Morales K.M., Morgan M.M., Munidasa M.M., Ngo D.N., Nguyen L.N.,
RA Nguyen T.N., Nguyen N.N., Obregon M.O., Okwuonu G.O., Ongeri F.O.,
RA Onwere C.O., Osifeso I.O., Parra A.P., Patil S.P., Perez A.P., Perez Y.P.,
RA Pham C.P., Pu L.-L.P., Puazo M.P., Quiroz J.Q., Rouhana J.R., Ruiz M.R.,
RA Ruiz S.-J.R., Saada N.S., Santibanez J.S., Scheel M.S., Schneider B.S.,
RA Simmons D.S., Sisson I.S., Tang L.-Y.T., Thornton R.T., Tisius J.T.,
RA Toledanes G.T., Trejos Z.T., Usmani K.U., Varghese R.V., Vattathil S.V.,
RA Vee V.V., Walker D.W., Weissenberger G.W., White C.W., Williams A.W.,
RA Woodworth J.W., Wright R.W., Zhu Y.Z., Han Y.H., Newsham I.N.,
RA Nazareth L.N., Worley K.W., Muzny D.M., Rogers J.R., Gibbs R.G.;
RT "Whole Genome Assembly of Papio anubis.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSPANP00000041804.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A2I3N1D0; -.
DR Ensembl; ENSPANT00000032535.2; ENSPANP00000041804.2; ENSPANG00000014202.3.
DR GeneTree; ENSGT00940000158502; -.
DR Proteomes; UP000028761; Chromosome 2.
DR Bgee; ENSPANG00000014202; Expressed in adrenal cortex and 66 other cell types or tissues.
DR ExpressionAtlas; A0A2I3N1D0; baseline.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00096; Ig; 2.
DR CDD; cd05763; IgI_LRIG1-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR45842:SF12; KEKKON 5, ISOFORM A; 1.
DR PANTHER; PTHR45842; SYNAPTIC ADHESION-LIKE MOLECULE SALM; 1.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF13855; LRR_8; 4.
DR Pfam; PF01463; LRRCT; 1.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 3.
DR SMART; SM00365; LRR_SD22; 5.
DR SMART; SM00369; LRR_TYP; 12.
DR SMART; SM00082; LRRCT; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50835; IG_LIKE; 3.
DR PROSITE; PS51450; LRR; 4.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028761};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 695..718
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 397..496
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 501..590
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 595..681
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 808..827
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 847..878
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 955..990
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..27
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 962..976
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 990 AA; 109117 MW; B0A054A60CD7FB0A CRC64;
MKRLTRKKQK VPDHRQRLRR QRRRQHNKIR SVEGSQLKAY LSLEVLDLSS NNITEVRNTC
FPHGPPIKEL NLAGNRIGTL ELGAFDGLSR SLLTLRLSKN RITQLPVRAF KLPRLTQLDL
NRNRIRLIEG LTFQGLNSLE VLKLQRNNIS KLTDGAFWGL SKMHVLHLEY NSLVEVNSGS
LYGLTALHQL HLSNNSIARI HRKGWSFCQK LHELVLSFNN LTRLDEESLA ELSSLSVLRL
SHNSISHIAE GAFKGLRSLR VLDLDHNEIA GTIEDTSGAF SGLDSLSKLT LFGNKIKSVA
KRAFSGLEGL EHLNLGGNAI RSVQFDAFVK MKNLKELHIS SDSFLCDCQL KWLPPWLMGR
MLQAFVTATC AHPESLKGQS IFSVPPESFV CDDFLKPQII TQPETTMAMV GKDIRFTCSA
ASSSSSPMTF AWKKDNEVLT NADMENFVHV HAQDGEVMEY TTILHLRQVT FGHEGRYQCV
ITNHFGSTYS HKARLTVNVL PSFTKTPHDI TIRTTTMARL ECAATGHPNP QIAWQKDGGT
DFPAARERRM HVMPDDDVFF ITDVKIDDAG VYSCTAQNSA GSISANATLT VLETPSLAVP
LEDRVVSAGE TVALQCKATG NPPPRITWFK GDRPLSLTER HHLTPDNQLL VVQNVVAEDA
GRYTCEMSNT LGTERAHSQL SVLPAAGCRK DGTTVGIFTI AVVSSIVLTS LVWVCIIYQT
RKKSEEYSVT NTDETIVPPD VPSYLSSQGT LSDRQETVVR TEGGPQANGH IESNGVCPRD
ASHFPEADAH SVACRQPKLC TGYHKEPWKA TEKAEGTPGP QKMEHGGRVV CSDCNTEVDC
YSREQDFHPQ PVSRDSVQPN GPEPGGSDQE HFPHHQCSGT AAGSCPECQG SLYPSNHDRM
LTAVKKKPVA SLDGKGDSSW TLARLYDPDY AELQPASSLT SGSPERTAAQ HLLVSNGHLP
KACDSSPEST PLTGQLPGKQ RVPLLLAPKS
//
